Ophthalmic orbital surgery apparatus and method and image-guide navigation system

• US 8,403,828 B2
• Filed: 07/21/2004
• Issued: 03/26/2013
• Est. Priority Date: 07/21/2003
• Status: Active Grant

• Current Assignee: Vanderbilt University
• Original Assignee: Vanderbilt University
• Inventors: Mawn, Louise A., Galloway, Robert L. Jr.
• Primary Examiner(s): SMITH, PHILIP ROBERT
• Application Number:
  US10/895,635
• Publication Number:
  US 20050054900A1
• Time in Patent Office: 3,170 Days
• Field of Search: 600/103, 600/109, 600117-118, 600/145
• US Class Current: 600/117
• CPC Class Codes: A61B 1/012 characterised by internal passages or accessories therefor
• CPC Class Codes: A61B 1/3132 for laparoscopy
• CPC Class Codes: A61B 2034/107 Visualisation of planned trajectories or target regions
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2034/2055 Optical tracking systems
• CPC Class Codes: A61B 2034/2072 Reference field transducer attached to an instrument or patient
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/064 using markers A61B5/062 takes precedence
• CPC Class Codes: A61B 5/065 Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
• CPC Class Codes: A61B 90/361 Image-producing devices, e.g. surgical cameras
• CPC Class Codes: A61F 2009/00851 Optical coherence topography [OCT]
• CPC Class Codes: A61F 2009/00897 Scanning mechanisms or algorithms
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/008 using laser
• CPC Class Codes: A61F 9/00802 for photoablation
• CPC Class Codes: A61F 9/00821 for coagulation

Abstract

A flexible endoscope for ophthalmic orbital surgery includes a flexible probe housing having a proximal end, a distal end and a lumen extending between the proximal end and the distal end. The endoscope also includes an image fiber disposed in the lumen that communicates image information from the distal end of the flexible probe, a purge fluid/gas port disposed at the proximal end of the flexible probe that accepts purge fluid/gas and a purge fluid/gas conduit disposed in the lumen and in fluid communication with the purge fluid/gas port. The fluid/gas conduit delivers purge fluid/gas to the distal end of the endoscope. The endoscope also includes an access conduit disposed in the lumen that receives one of an ablation instrument, a coagulating instrument and a medication delivery instrument.

Claims

1. An apparatus for collecting and processing physical space data for use while performing image-guided surgery with an instrument, the apparatus comprising:

(a) an endoscope including;

(i) a probe housing having a proximal end, a distal end and a lumen extending between the proximal end and the distal end;

(ii) an image fiber disposed in the lumen that communicates image information from the distal end;

(iii) a purge fluid/gas port disposed at the proximal end of the probe that accepts purge fluid/gas;

(iv) a purge fluid/gas conduit disposed in the lumen and in fluid communication with the purge fluid/gas port, the conduit delivering purge fluid/gas to the distal end of the endoscope; and

(v) an access conduit disposed in the lumen which receives the instrument;

(b) a magnetic tracking system that includes a magnetic tracking tip disposed proximate the distal end of the probe housing and that is configured to detect the magnetic tracking tip in a three dimensional (3-D) physical space; and

(c) an image data processor configured to

obtain an image space having a plurality of tomographic images each containing all image information;

determine point-based registrations mapping the 3-D physical space to the image space based on points in the 3-D physical space and corresponding points in the image space;

determine a location and an orientation of the instrument in the image space based on magnetic tracking tip location data generated by the magnetic tracking tip in the 3-D physical space and the point-based registrations; and

dynamically display, while performing the image-guided surgery, (i) a selected one of the plurality of the tomographic images that overlaps the location of the instrument in the image space and (ii) indications of the location and orientation of the instrument in the image space.

2. The apparatus of claim 1, further comprising:

(d) a scanning device for scanning tissue of the patient to acquire, store and process a 3-D reference of tissue prior to the tissue being surgically exposed, wherein the image data processor creates a triangularized mesh based on the scanned tissue, determines the volumetric center of a particular portion of the tissue to be ablated, coagulated or medicated during the surgery, and implements an algorithm using the triangularized mesh and the physical space data collected by the instrument to determine the point-based registrations, wherein the instrument is configured to transmit a free electron laser (FEL) that surgically ablates a particular portion of a tissue.

3. The apparatus of claim 2, wherein the scanning device is one of the following scanners:

a computerized tomography (CT) scanner, a magnetic resonance imaging (MRI) scanner and a positron emission tomography (PET) scanner image space, wherein the instrument includes a laser delivery system including a waveguide and a lens mounted to a distal end of the waveguide adjacent to the distal end of the endoscope, wherein a proximal end of the waveguide is coupled to a laser source, wherein the laser source that is a FEL source generating FEL in a predetermined wavelength range including 6.45 μ

m, wherein the waveguide is a glass hollow waveguide adapted for transmitting FEL in a predetermined wavelength range including 6.45 μ

m.

4. The apparatus of claim 1, wherein the magnetic tracking tip location data includes <

x, y, z>

positional coordinates and orientation angles and a rotation matrix, wherein the image space includes scanned images that are previously obtained, wherein the image data processor provides the scanned images for display while the image-guided surgery is being performed, wherein the instrument is configured to transmit a free electron laser that surgically ablates a particular portion of a tissue.

5. The apparatus of claim 1, wherein points from 3-D physical space are mapped to 2-dimensional (2-D) image space, wherein the instrument includes a laser delivery system including a waveguide and a lens mounted to a distal end of the waveguide adjacent to the distal end of the endoscope, wherein a proximal end of the waveguide is coupled to a laser source, wherein the laser source that is a free electron laser (FEL) source generating FEL in a predetermined wavelength range including 6.45 μ

m, wherein the waveguide is adapted for transmitting FEL in a predetermined wavelength range including 6.45 μ

m.

6. The apparatus of claim 5, further comprising a display device, wherein the display device is configured to display the 2-dimensional image space.

7. The apparatus of claim 6, wherein the display device is operatively connected to the endoscope.