Electroporation ablation apparatus, system, and method
First Claim
1. An ablation device, comprising:
- an elongate member comprising first and second channels;
first and second probes disposed within the respective first and second channels, the first and second probes each defining a central axis, the first and second probes each having substantially straight distal ends protruding from the distal ends of the respective first and second channels, the substantially straight distal ends defining an outer surface; and
first and second electrodes attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes;
the first and second electrodes positioned in juxtaposed relationship with the central axis of the first and second probes;
wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes;
wherein the substantially straight distal end of the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough.
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Accused Products
Abstract
A surgical instrument, such as an endoscopic or laparoscopic instrument, includes an ablation device. The ablation device includes an elongate member having first and second channels. First and second probes are disposed within the respective first and second channels. The first and second probes each define a central axis. The first and second probes each have substantially straight distal ends protruding from the distal ends of the respective first and second channels. The substantially straight distal ends define an outer surface. First and second electrodes are attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes. The first and second electrodes are positioned in juxtaposed relationship with the central axis of the first and second probes. A distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes.
1507 Citations
23 Claims
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1. An ablation device, comprising:
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an elongate member comprising first and second channels; first and second probes disposed within the respective first and second channels, the first and second probes each defining a central axis, the first and second probes each having substantially straight distal ends protruding from the distal ends of the respective first and second channels, the substantially straight distal ends defining an outer surface; and first and second electrodes attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes; the first and second electrodes positioned in juxtaposed relationship with the central axis of the first and second probes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes; wherein the substantially straight distal end of the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An ablation system, comprising:
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an elongate member comprising first and second channels; first and second probes disposed within the respective first and second channels, the first and second probes each defining a central axis, the first and second probes each having substantially straight distal ends protruding from the distal ends of the respective first and second channels, the substantially straight distal ends defining an outer surface; first and second electrodes attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes; the first and second electrodes positioned in juxtaposed relationship with the central axis of the first and second probes; and an electrical waveform generator electrically coupled to the first and second electrodes to generate an irreversible electroporation electrical (IRE) waveform sufficient to ablate tissue located proximate to the first and second electrodes; wherein a distance between the first and second electrodes is adjustable by rotating at least one of the first and second probes about the respective central axis of the at least one of the first and second probes; wherein the substantially straight distal end of the first probe comprises a sharp distal end and an aperture in communication with a bore formed within the first probe to receive a tissue sample therethrough. - View Dependent Claims (8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method, comprising:
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locating an elongate member comprising first and second channels within a body cavity proximate to a tissue treatment region, wherein the first and second probes are disposed within the respective first and second channels, the first and second probes each defining a central axis, the first and second probes each having substantially straight distal ends protruding from the distal ends of the respective first and second channels, the substantially straight distal ends defining an outer surface;
wherein the first and second electrodes are attached to a portion of the outer surface of the substantially straight distal ends of the respective first and second probes;
the first and second electrodes positioned in juxtaposed relationship with the central axis of the first and second probes;adjusting a distance between the first and second electrodes by rotating at least one of the first and second probes about the central axis of the at least one of the first and second probes; and receiving a tissue sample through a sharp distal end and an aperture in communication with a bore formed within either one of the first and second probes. - View Dependent Claims (18, 19, 20, 21, 22, 23)
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Specification