Treatment with anti-ErbB2 antibodies

  • US 8,425,908 B2
  • Filed: 07/18/2011
  • Issued: 04/23/2013
  • Est. Priority Date: 12/12/1997
  • Status: Expired due to Fees
First Claim
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1. A method for the treatment of a human patient with gastric cancer characterized by overexpression of ErbB2 receptor, comprising administering an effective amount of a combination of an anti-ErbB2 antibody, or an antigen-binding fragment thereof, and a chemotherapeutic agent, to the human patient, wherein the chemotherapeutic agent is capecitabine or 5-fluorouracil, wherein the attending physician is provided with instructions including a warning that the treatment is not to be performed in combination with an anthracycline derivative and wherein said antibody binds to epitope 4D5 within the ErbB2 extracellular domain sequence.

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