Testosterone gel and method of use

  • US 8,466,137 B2
  • Filed: 07/11/2011
  • Issued: 06/18/2013
  • Est. Priority Date: 10/12/2005
  • Status: Active Grant
First Claim
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1. A method of treating hypogonadism in a human male in need thereof comprising the step of:

  • a) applying a therapeutically effective dose of a hydroalcoholic gel to an area of skin of a human male, the hydroalcoholic gel consisting of;

    i) 1.3% to 1.7% (w/w) testosterone;

    ii) 0.9% to 1.0% (w/w) isopropyl myristate;

    iii) 67.0% to 74.0% (w/w) of a lower alcohol selected from the group consisting of;

    methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, sec-butanol and tert-butanol;

    iv) 0.6% to 1.4% (w/w) of a polyacrylic acid;

    v) 1.0% to 10.0% (w/w) of 0.1 N sodium hydroxide; and

    vi) water.

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