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Transient decay amperometry

  • US 8,470,604 B2
  • Filed: 08/16/2011
  • Issued: 06/25/2013
  • Est. Priority Date: 10/24/2006
  • Status: Active Grant
First Claim
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1. A method for determining an analyte concentration in a sample, comprising:

  • reacting an analyte in a sample with an ionizing agent;

    forming a measurable species from the reaction between the sample and the ionizing agent during an incubation period from 0.1 to 8 seconds, where the measurable species concentration in the sample is responsive to an analyte concentration in the sample;

    applying an input signal to the sample after the incubation period, where the input signal includes excitations and relaxations, whereat least two of the excitations have a duration from 0.1 to 5 seconds, and whereat least one of the relaxations has a duration from 0.4 to 1 second;

    generating an output signal from the excitation following the at least one of the relaxations having the duration from 0.4 to 1 second, the output signal having a transient decay responsive to a redox reaction of the measurable species; and

    determining the analyte concentration of the sample from the transient decay of the generated output signal.

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