Analyte sensor with time lag compensation
First Claim
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1. A method, comprising:
- determining a predetermined time period characterized with a rate of change of an analyte level below a preset threshold;
defining a data set associated with a monitored analyte level within the predetermined time period;
determining a sensitivity value based on the defined data set;
applying, using one or more processors, the determined sensitivity value to signals associated with the monitored analyte level including the defined data set;
estimating, using the one or more processors, a time constant, associated with an analyte sensor used to monitor the analyte level, using reference data, the monitored analyte level, and the rate of change of the monitored analyte level;
performing, using the one or more processors, lag correction of the signals associated with the monitored analyte level based on the estimated time constant; and
calibrating, using the one or more processors, the lag corrected signals to estimate a corresponding monitored glucose level.
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Abstract
Methods and devices and systems for determining an analyte value are disclosed.
658 Citations
22 Claims
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1. A method, comprising:
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determining a predetermined time period characterized with a rate of change of an analyte level below a preset threshold; defining a data set associated with a monitored analyte level within the predetermined time period; determining a sensitivity value based on the defined data set; applying, using one or more processors, the determined sensitivity value to signals associated with the monitored analyte level including the defined data set; estimating, using the one or more processors, a time constant, associated with an analyte sensor used to monitor the analyte level, using reference data, the monitored analyte level, and the rate of change of the monitored analyte level; performing, using the one or more processors, lag correction of the signals associated with the monitored analyte level based on the estimated time constant; and calibrating, using the one or more processors, the lag corrected signals to estimate a corresponding monitored glucose level. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An apparatus, comprising:
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a data communication interface; one or more processors operatively coupled to the data communication interface; and a memory storing instructions which, when executed by the one or more processors, causes the one or more processors to determine a predetermined time period characterized with a rate of change of an analyte level below a preset threshold, define a data set associated with a monitored analyte level within the predetermined time period, determine a sensitivity value based on the defined data set, apply the determined sensitivity value to signals associated with the monitored analyte level including the defined data set, estimate a time constant, associated with an analyte sensor used to monitor the analyte level, using reference data, the monitored analyte level, and the rate of change of the monitored analyte level, perform lag correction of the signals associated with the monitored analyte level based on the estimated time constant, and calibrate the lag corrected signals to estimate a corresponding monitored glucose level. - View Dependent Claims (8, 9, 10, 11, 12)
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13. A computer implemented method, comprising:
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calibrating, using one or more processors, analyte data associated with a monitored analyte level received from an analyte sensor based on a reference measurement; determining, using the one or more processors, a rate of change of the monitored analyte level; determining, using the one or more processors, a lag time constant, associated with the calibrated analyte data, using the reference measurement, the monitored analyte level, and the rate of change of the monitored analyte level; and performing, using the one or more processors, lag correction of the calibrated analyte data based on the determined time lag constant. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22)
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Specification