Stent with anchors to prevent vulnerable plaque rupture during deployment

• US 8,475,518 B2
• Filed: 07/11/2007
• Issued: 07/02/2013
• Est. Priority Date: 12/22/2003
• Status: Active Grant

• Current Assignee: Advanced Cardiovascular Systems Incorporated
• Original Assignee: Advanced Cardiovascular Systems Incorporated
• Inventors: Cox, Daniel L., Feezor, Christopher
• Primary Examiner(s): MCEVOY, THOMAS M
• Application Number:
  US11/776,458
• Publication Number:
  US 20080015685A1
• Time in Patent Office: 2,183 Days
• Field of Search: 623/1.14, 623/1.15, 623/1.3, 623/1.36, 623/1.11, 623/1.12, 623 117- 12
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91575 connected peak to trough
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped

Abstract

A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.

Claims

1. A method for implanting a stent within a vessel including vulnerable plaque, comprising:

positioning a cylindrical stent in a crimped state within a lumen of a vessel having a vessel wall and near a target area including vulnerable plaque, the stent having a length and a circumference formed by cylindrical rings connected by links along a longitudinal axis of the stent, the stent further including a first region spanning an arc along the circumference and axially along the length of the stent, and a second region, excluding the first region, spanning the circumference and axially along the length of the stent, and the stent also including anchors positioned on an outer surface of the links only and within only a first transition and a second transition, the first transition and the second transition defining a border between the first region and the second region, each anchor being disposed between the first region and the second region along lines substantially parallel to the longitudinal axis of the stent;

aligning the first region of the stent to substantially cover the vulnerable plaque of the vessel;

visualizing the alignment of the stent within the vessel using guidance equipment;

expanding the first region until nearly fully deployed and the anchors are embedded into the vessel wall proximate to and on opposite sides of the vulnerable plaque; and

expanding the second region of the stent after nearly fully deploying the first region until the second region of the stent is fully deployed.

2. The method of claim 1, wherein when expanding the second region until it is fully deployed, the first transition and second transition are spread apart by about 90°

.

3. The method of claim 1, wherein the cylindrical rings comprise struts, the struts being in the first region and the second region, and the struts in the first region are weaker than the struts in the second region.

4. The method of claim 1, wherein the anchors are attached to the links so that as the stent expands radially outwardly, there is minimal circumferential movement of the anchors.

5. The method of claim 1, wherein the anchors have a height in the range of 50 microns to 100 microns.