Multibaseline PRF-shift magnetic resonance thermometry
First Claim
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1. A multibaseline method of performing proton resonance frequency (PRF) thermometry, the method comprising the steps of:
- acquiring a plurality of PRF baseline images of an imaging region, each baseline image corresponding to a PRF phase background during the imaging region'"'"'s cycle of motion;
acquiring a PRF treatment image of the imaging region subsequent to temperature change of a subregion within the imaging region;
estimating a phase background of the imaging region by fitting a combination of the PRF baseline images to the treatment image; and
estimating a temperature distribution within the subregion based on the treatment image and the estimated phase background.
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Abstract
The phase background of a proton resonance frequency shift treatment image may be estimated by fitting a combination of baseline images to the treatment image.
54 Citations
18 Claims
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1. A multibaseline method of performing proton resonance frequency (PRF) thermometry, the method comprising the steps of:
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acquiring a plurality of PRF baseline images of an imaging region, each baseline image corresponding to a PRF phase background during the imaging region'"'"'s cycle of motion; acquiring a PRF treatment image of the imaging region subsequent to temperature change of a subregion within the imaging region; estimating a phase background of the imaging region by fitting a combination of the PRF baseline images to the treatment image; and estimating a temperature distribution within the subregion based on the treatment image and the estimated phase background. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A system for performing multibaseline proton resonance frequency (PRF) shift thermometry, the system comprising:
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(a) a magnetic resonance imaging (MRI) unit; (b) a control module in communication with the MRI unit and configured to cause the MRI unit to; acquire a plurality of PRF baseline images of an imaging region, each baseline image corresponding to a PRF phase background during the imaging region'"'"'s cycle of motion; acquire a PRF treatment image of the imaging region subsequent to temperature change of a subregion within the imaging region; estimate a phase background of the imaging region by fitting a combination of the PRF baseline images to the treatment image; and estimate a temperature distribution within the subregion based on the treatment image and the estimated phase background; and (c) a display for displaying the temperature distribution.
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Specification