Multiple chamber container

• US 8,485,727 B2
• Filed: 08/02/2006
• Issued: 07/16/2013
• Est. Priority Date: 08/02/2005
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Desbrosses, Freddy, Bonnot, Denis, Melin, Christian, Trouilly, Jean Luc
• Primary Examiner(s): Pascua, Jes F
• Application Number:
  US11/461,963
• Publication Number:
  US 20070029001A1
• Time in Patent Office: 2,540 Days
• Field of Search: 383/38, 383/93, 383/94, 383/39, 383/210, 383/211, 383/9, 206/828, 206/219, 141/114, 604408-410, 604/82, 604/85, 604/87, 604/89, 604/90
• US Class Current: 383/38
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A23L 33/115 Fatty acids or derivatives thereof; Fats or oils
• CPC Class Codes: A23L 33/16 Inorganic salts, minerals or trace elements
• CPC Class Codes: A23L 33/17 Amino acids, peptides or proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/1462 Containers with provisions for hanging, e.g. integral adaptations of the container accessories for hanging the container A61M5/1414
• CPC Class Codes: A61J 1/2024 having peelable seals
• CPC Class Codes: A61J 1/2093 Containers having several compartments for products to be mixed
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/198 Alpha-amino acids, e.g. alanine or edetic acid [EDTA] betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00
• CPC Class Codes: A61K 33/00 Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 36/63 Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
• CPC Class Codes: A61K 45/06 Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• CPC Class Codes: A61K 9/0019 Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner non-active ingredients are additionally classified in A61K47/00
• CPC Class Codes: A61P 3/02 Nutrients, e.g. vitamins, minerals
• CPC Class Codes: B32B 27/08 of synthetic resin
• CPC Class Codes: G01N 21/783 for analysing gases
• CPC Class Codes: G01N 31/225 for oxygen, e.g. including dissolved oxygen

Abstract

A multiple chamber container for separately storing components of a parenteral nutritional formulation is provided. The multiple chamber container may include frangible barriers, preferably peelable seals separating the chambers from each other. The container preferably facilitates the selective activation of the peelable seals to permit the admixing of less than all the separately stored components. The container may include a chamber positioned at each of the opposite lateral ends of the container and at least one additional chamber between the lateral chambers. The at least one additional chamber may have a longitudinal length substantially less than the longitudinal length of at least one of the lateral chambers. This configuration allows for selective opening of the seals since when rolling the container from the top avoids pressurizing the at least one additional chamber and inadvertent activation of a seal. The longitudinal length of the at least one additional chamber may be from about two-thirds to about three-fourths the longitudinal length of at least one of the lateral chambers. Alternatively, the container may include a hanger flap extending from a top end of the container towards the bottom end a substantially greater distance relative to the at least one additional chamber than the lateral chambers.

Claims

1. A flexible multilayer bag for storing and admixing medical products comprising:

a) top, bottom, first and second lateral sides;

b) a first chamber, a middle chamber, and a third chamber, the middle chamber having a longitudinal length that is from about two-thirds to about three-quarters of longitudinal lengths of the first and third chambers;

c) a first frangible barrier separating the first and middle chambers and a second frangible barrier separating the middle and third chambers;

d) a flap defining straight borders of upper ends of the first chamber, middle chamber and third chamber; and

e) at least two ports located at the bottom side, each port providing access to a different one of the first, middle, and third chambers wherein the first, middle and third chambers are arranged such that rolling the bag from the top side allows selective activation of one of the first and second frangible barriers without activating the other of the first and second frangible barriers.

2. The flexible multilayer bag of claim 1 wherein the first and second frangible barriers are peelable seals.

3. The multilayer bag of claim 1 further including three ports, each port providing fluid communication with a different one of the first, middle, and third chambers.

4. The multilayer bag of claim 3 further including a component of a parenteral formulation for fluid restricted patients in each of the first, middle and third chambers wherein one of the components includes cysteine.

5. The multilayer bag of claim 4 wherein the flap includes an opening for hanging the multilayer bag on a stand or hook.

6. The flexible multilayer bag of claim 1, wherein the first chamber is positioned adjacent to one of the first and second lateral sides, and wherein the third chamber is positioned adjacent the other of the first and second lateral sides.

7. A flexible multilayer bag for storing and admixing medical products comprising:

a) top, bottom, left, and right sides;

b) a first chamber, a second chamber, and a third chamber, the first and second chambers having longitudinal lengths that differ from each other by a degree of about twenty five percent to about thirty three percent, the second and third chambers having longitudinal lengths that differ from each other by a degree of about twenty five percent to about thirty three percent;

c) a plurality of frangible barriers separating the first, second and third chambers from each other;

d) a flap defining a straight border of upper ends of the first, second and third chambers; and

e) at least two ports located at the bottom side, each port providing access to a different one of the first, second, and third chambers wherein the first, second and third chambers are arranged such that rolling the bag starting at an intersection between the top side and one of the left and right sides allows selective activation of one of the frangible barriers without activating the other of the frangible barriers.

8. The flexible multilayer bag of claim 7 wherein the plurality of frangible barriers are peelable seals.

9. The flexible multilayer bag of claim 7 further including a third port providing fluid communication with the other of the first and second chambers.

10. The flexible multilayer bag of claim 7, wherein the first chamber is positioned adjacent to one of the left and right sides, and wherein the third chamber is positioned adjacent to the other of the left and right sides.