Methods of modifying eukaryotic cells

CAFC
  • US 8,502,018 B2
  • Filed: 06/20/2011
  • Issued: 08/06/2013
  • Est. Priority Date: 10/31/2000
  • Status: Expired due to Term
First Claim
Patent Images

1. A genetically modified mouse, comprising in its germline human unrearranged variable region gene segments inserted at an endogenous mouse immunoglobulin locus.

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