Systems and methods using induced perturbation to determine physiological parameters
First Claim
1. A method for monitoring blood pressure comprising:
- inducing a perturbation signal in a subject'"'"'s body;
detecting a signal from the subject'"'"'s body;
transforming the detected signal using a continuous wavelet transform to generate a scalogram, wherein the scalogram comprises three dimensional data, wherein a first dimension of the scalogram corresponds to time, wherein a second dimension of the scalogram corresponds to scale, and wherein a third dimension of the scalogram corresponds to phase;
determining, from the scalogram, a phase that corresponds to a particular time and scale;
determining, based at least in part on the phase and the perturbation signal, a phase difference; and
determining, based at least in part on the determined phase difference, a blood pressure measurement.
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Abstract
According to embodiments, systems and methods for non-invasive blood pressure monitoring are disclosed. An exciter may induce perturbations in a subject, and a sensor or probe may be used to obtain a detected signal from the subject. The detected signal may then be used to measure one or more physiological parameters of the patient. For example if the perturbations are based on a known signal, any differences between the known signal and the input signal may be attributable to the patient'"'"'s physiological parameters. A phase drift between the perturbation signal and the detected signal may be determined from a comparison of the scalograms of the exciter location and the sensor or probe location. From the scalogram comparison, more accurate and reliable physiological parameters may be determined.
258 Citations
23 Claims
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1. A method for monitoring blood pressure comprising:
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inducing a perturbation signal in a subject'"'"'s body; detecting a signal from the subject'"'"'s body; transforming the detected signal using a continuous wavelet transform to generate a scalogram, wherein the scalogram comprises three dimensional data, wherein a first dimension of the scalogram corresponds to time, wherein a second dimension of the scalogram corresponds to scale, and wherein a third dimension of the scalogram corresponds to phase; determining, from the scalogram, a phase that corresponds to a particular time and scale; determining, based at least in part on the phase and the perturbation signal, a phase difference; and determining, based at least in part on the determined phase difference, a blood pressure measurement. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A system for monitoring blood pressure comprising:
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an exciter capable of inducing a perturbation signal in a subject'"'"'s body; a sensor capable of generating a detected signal from the subject'"'"'s body; and a processor capable of; transforming the detected signal using a continuous wavelet to generate a scalogram, wherein the scalogram comprises three dimensional data, wherein a first dimension of the scalogram corresponds to time, wherein a second dimension of the scalogram corresponds to scale, and wherein a third dimension of the scalogram corresponds to phase; determining, from the scalogram, a phase that corresponds to a particular time and scale; determining, based at least in part on the phase and the perturbation signal, a phase difference; and determining, based at least in part on the determined phase difference, a blood pressure measurement. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A non-transitory computer-readable medium for use in detecting an artifact in a signal, the computer-readable medium having computer program instructions recorded thereon for:
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inducing a perturbation signal in a subject'"'"'s body; detecting a signal from the subject'"'"'s body; transforming the detected signal using a continuous wavelet transform to generate a scalogram, wherein the scalogram comprises three dimensional data, wherein a first dimension of the scalogram corresponds to time, wherein a second dimension of the scalogram corresponds to scale, and wherein a third dimension of the scalogram corresponds to phase; determining, from the scalogram, a phase that corresponds to a particular time and scale; determining, based at least in part on the phase and the perturbation signal, a phase difference; and determining, based at least in part on the determined phase difference, a blood pressure measurement.
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Specification