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Methods of treating hypertriglyceridemia

DC CAFC
  • US 8,524,698 B2
  • Filed: 02/25/2013
  • Issued: 09/03/2013
  • Est. Priority Date: 02/10/2009
  • Status: Active Grant
First Claim
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1. A method of reducing triglycerides comprising, orally administering daily for a period of at least about 12 weeks to a subject having a fasting baseline triglyceride level of at least 500 mg/dl a pharmaceutical composition comprising about 4 g of ethyl eicosapentaenoate and not more than about 4% docosahexaenoic acid or its esters, by weight of all fatty acids, wherein the pharmaceutical composition, when administered for twelve weeks to a first patient population having said baseline triglyceride level is effective to reduce a median triglyceride level in the first patient population by at least about 25% compared to a median triglyceride level observed in a second patient population having said baseline triglyceride level who has not received the pharmaceutical composition.

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