Device and method for determining analyte levels

  • US 8,527,025 B1
  • Filed: 11/22/1999
  • Issued: 09/03/2013
  • Est. Priority Date: 03/04/1997
  • Status: Expired due to Fees
First Claim
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1. A device for measuring a glucose concentration in a host, the device comprising:

  • a sensor operably connected to an electronic circuit and configured to continuously measure a signal associated with a glucose concentration in a host; and

    a membrane located over at least a portion of the sensor, wherein the membrane is configured to control a flux of oxygen and glucose, wherein the membrane is configured to use oxygen from a biological fluid surrounding the membrane to catalyze a reaction of glucose and oxygen, and wherein the membrane comprises a silicone-containing polymer;

    wherein the device is capable of exhibiting, at a glucose concentration of 400 mg/dL, no more than a 10% drop in sensor output over a range of pO2 from about 150 mm Hg down to about 30 mm Hg.

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