Ocular implant applier and methods of use

• US 8,535,333 B2
• Filed: 07/29/2010
• Issued: 09/17/2013
• Est. Priority Date: 07/29/2009
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Transcend Medical Incorporated (Alcon Incorporated)
• Inventors: de Juan, Eugene Jr., John, Steven, Garcia, Jose, Lilly, Richard S., Silvestrini, Thomas A.
• Primary Examiner(s): MCEVOY, THOMAS M
• Application Number:
  US12/846,201
• Publication Number:
  US 20110112546A1
• Time in Patent Office: 1,146 Days
• Field of Search: 606/107, 606/161, 606/166, 606/108, 623/6.12, 623/23.64, 623/23.7, 604/8
• US Class Current: 606/108
• CPC Class Codes: A61B 2090/061 for measuring dimensions, e.g. length
• CPC Class Codes: A61B 2090/062 penetration depth
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: A61F 9/007 Methods or devices for eye surgery
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Described herein is a delivery device and methods for delivering an ocular implant into an eye. The delivery device includes a proximal handle portion; a distal delivery portion coupled to a distal end of the handle portion and configured to releasably hold an ocular implant and includes a sheath positioned axially over a guidewire; and a metering system configured to provide visual guidance regarding depth of advancement of an implant positioned on the guidewire into an anatomic region of the eye. Also disclosed is a device and method for loading an implant onto the delivery device.

Claims

1. A method of using a delivery system for implantation of a device into an eye in the absence of a lens or other imaging system, the method comprising:

mounting an implant on a delivery device comprising a guidewire having a sheath coupled to the guidewire, wherein the guidewire comprises a first metering system at a distal end of the guidewire and the sheath comprises a second metering system at a distal end of the sheath, the first and second metering systems having corresponding graduated markings;

inserting the implant on the delivery device into an anterior chamber through an incision in a cornea;

advancing the implant on the delivery device through a transparent zone of the anterior chamber toward an opaque zone of the anterior chamber;

seating a distal end of the guidewire at eye tissue where resistance is felt;

reading through the transparent zone a first graduated marking of the first metering system, wherein the first graduated marking is aligned with an edge between the transparent zone and the opaque zone;

advancing the implant on the guidewire into the eye tissue beyond where resistance is felt; and

reading through the transparent zone a second graduated marking on the second metering system, wherein the second graduated marking is aligned with the edge between the transparent zone and the opaque zone.

2. The method of claim 1, further comprising releasing the implant from the guidewire.

3. The method of claim 2, wherein the implant provides a flow passageway between the anterior chamber and the suprachoroidal space.

4. The method of claim 1, wherein inserting the implant comprises inserting the entire implant into the anterior chamber.

5. The method of claim 1, wherein the first metering system further comprising a blank band at the distal end region of the guidewire having a width.

6. The method of claim 5, wherein the width of the blank band corresponds to a width of the implant remaining within the anterior chamber once the implant is inserted into the eye tissue.

7. The method of claim 1, further comprising retaining the implant on the guidewire using a polymeric retention coating.

8. The method of claim 1, wherein seating a distal end of the guidewire at eye tissue where resistance is felt comprises seating the guidewire with a portion of the ciliary body having a tissue border with the scleral spur.

9. The method of claim 1, wherein advancing the implant on the guidewire into the eye tissue beyond where resistance is felt comprises positioning a distal end of the implant at least partially between a portion of the ciliary body and a portion of the sclera within a supraciliary space.

10. The method of claim 1, wherein advancing the implant on the guidewire into the eye tissue beyond where resistance is felt comprises positioning a distal end of the implant at least partially between a portion of the choroid and a portion of the sclera within a suprachoroidal space.