Process for the preparation of roflumilast

  • US 8,536,206 B2
  • Filed: 07/12/2012
  • Issued: 09/17/2013
  • Est. Priority Date: 03/10/2003
  • Status: Active Grant
First Claim
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1. A method for the treatment of chronic obstructive pulmonary disease, comprising:

  • administering to a patient suffering from chronic obstructive pulmonary disease N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-hydroxybenzamide and a therapeutically effective amount of roflumilast.

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