Optimized dengue virus entry inhibitory peptide (DN81)
First Claim
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1. A synthetic peptide comprising:
- an amino acid sequence presented as SEQ ID NO;
1.
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Abstract
The invention relates peptide entry inhibitors and methods of determining such inhibitors that are bindable to regions of viruses having class II E proteins, such as the dengue virus E protein, as candidates for in vivo anti-viral compounds.
2 Citations
13 Claims
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1. A synthetic peptide comprising:
- an amino acid sequence presented as SEQ ID NO;
1. - View Dependent Claims (2, 3, 4, 5, 6, 7)
- an amino acid sequence presented as SEQ ID NO;
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8. A method of treating dengue virus infection in a subject comprising the steps of:
- administering a therapeutically effective amount of the peptide comprising the amino acid sequence presented as SEQ ID NO;
1 to a subject in need thereof. - View Dependent Claims (9, 10, 11, 12, 13)
- administering a therapeutically effective amount of the peptide comprising the amino acid sequence presented as SEQ ID NO;
Specification