Treatment of pain with topical diclofenac compounds

  • US 8,546,450 B1
  • Filed: 07/10/2009
  • Issued: 10/01/2013
  • Est. Priority Date: 03/31/2009
  • Status: Active Grant
First Claim
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1. A method for treating a patient with combination therapy, said combination therapy comprising:

  • administering a therapeutically effective amount of an oral NSAID; and

    applying a topical diclofenac preparation to a knee of said patient to treat osteoarthritis of the knee of said patient, wherein said topical diclofenac preparation comprises a therapeutically effective amount of a diclofenac salt and 40-50% w/w dimethyl sulfoxide,wherein the therapeutically effective amount of oral NSAID is the amount required to achieve a therapeutic effect in the absence of applying a topical diclofenac preparation.

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