Microfluidic connector

• US 8,550,503 B2
• Filed: 09/27/2007
• Issued: 10/08/2013
• Est. Priority Date: 09/28/2006
• Status: Expired due to Fees

• Current Assignee: Stokes Bio Ltd. (Perspecta, Inc.)
• Original Assignee: Stokes Bio Ltd. (Perspecta, Inc.)
• Inventors: Davies, Mark, Dalton, Tara
• Primary Examiner(s): BOCHNA, DAVID
• Application Number:
  US12/443,303
• Publication Number:
  US 20100109320A1
• Time in Patent Office: 2,203 Days
• Field of Search: 285/302, 285/124.3, 210/461, 210/460, 210/462, 422/502, 422/546
• US Class Current: 285/302
• CPC Class Codes: B01L 2200/027 for microfluidic devices
• CPC Class Codes: B01L 3/5027 by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip B01L3/5023 takes precedence; micromixers B01F33/30; microreactors for synthesis B01J19/0093; microcapillary devices in general B81B1/00
• CPC Class Codes: B01L 3/5635 connecting two containers face to face, e.g. comprising a filter
• CPC Class Codes: B01L 3/565 Seals in general F16L
• CPC Class Codes: F16L 39/00 Joints or fittings for double-walled or multi-channel pipes or pipe assemblies
• CPC Class Codes: F16L 41/18 the branch pipe being movable
• CPC Class Codes: Y10T 137/0318 Processes

Abstract

A microfluidic connector (1) comprises an enclosure (6, 7), a fluidic inlet port (2) and a fluidic outlet port (3), in the enclosure, in which the inlet and outlet ports (2, 3) are movable with respect to each other, for example, mutual spacing between the inlet and outlet ports (2, 3) is variable. A port (2) is in a fixed part (6) of the enclosure, and another port (3) is in a part (7) of the enclosure which slides with respect to the fixed part. There may be multiple inlet ports (22, 23) and/or multiple outlet ports (24, 25). Also, there may be an auxiliary port (45) for introduction of fluid into the enclosure (47, 48) or removal of fluid from the enclosure.

Claims

1. A fluidic connector comprising

an enclosure comprising a fixed part and a movable part, wherein the enclosure includes a first fluid, the enclosure is enclosed within an outer enclosure, and wherein there is a port in the enclosure for flow of fluid between the enclosure and outer enclosure;

a fluidic inlet port, located within the fixed part, for introducing a second fluid, wherein the second fluid is immiscible with the first fluid; and

a fluidic outlet port located within the movable part,

wherein the fluidic inlet port and the fluidic outlet port are not physically connected and wherein the fluidic inlet port and the fluidic outlet port are in fluidic communication with the enclosure.

2. The fluidic connector of claim 1, wherein the mutual spacing between the inlet and outlet ports is variable.

3. The fluidic connector of claim 1, wherein the movable part slides within the fixed part.

4. The fluidic connector of claim 1, wherein the connector comprises a plurality of inlet ports.

5. The fluidic connector of claim 1, wherein the connector comprises a plurality of outlet ports.

6. The fluidic connector of claim 1 further comprising an auxiliary port for the introduction of fluid into the enclosure or removal of fluid from the enclosure.

7. The fluidic connector of claim 1, wherein the connector comprises a single inlet port and a plurality of outlet ports, the enclosure being configured as a manifold.

8. The fluidic connector of claim 1, wherein the connector comprises a single outlet port and a plurality of inlet ports, the enclosure being configured as a mixer.

9. The fluidic connector of claim 1, wherein the outer enclosure has an outlet port.

10. The fluidic connector of claim 1, wherein there are a plurality of enclosures within the outer enclosure.

11. A method of controlling fluidic flow through the connector of claim 1, the method comprising the steps of directing flow of a carrier fluid carrying discrete plugs or droplets of a different fluid so that the plugs or droplets transfer from the inlet port to the outlet port.