Gas-pressured medication delivery device

• US 8,551,071 B2
• Filed: 03/18/2011
• Issued: 10/08/2013
• Est. Priority Date: 03/19/2010
• Status: Expired due to Fees

• Current Assignee: Halozyme, Inc. (Halozyme Therapeutics, Inc.)
• Original Assignee: Halozyme, Inc. (Halozyme Therapeutics, Inc.)
• Inventors: Hwang, Chorng-Fure Robin, Moore, David, Zeis, John
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): CARPENTER, WILLIAM R
• Application Number:
  US13/051,719
• Publication Number:
  US 20110238037A1
• Time in Patent Office: 935 Days
• Field of Search: 604/156, 604/30, 604/65, 604/131, 604/132, 604/140, 604/141, 604145-147, 604/31, 604 66- 71, 604/118, 604/151, 604/153, 604/246, 604/500, 604/506
• US Class Current: 604/506
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14256 with means for preventing access to the needle after use
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/2455 with sealing means to be broken or opened
• CPC Class Codes: A61M 5/31501 Means for blocking or restricting the movement of the rod or piston A61M5/5013 takes precedence

Abstract

The present invention relates to medical devices and particularly to a medication delivery device for self-injection of a medication, or for healthcare professionals to administer a medication. In one embodiment, a medication delivery device utilizes a source of gas pressure to deploy a needle, deliver a desired amount of medication through the needle, and retract the needle for disposal. Fluid flow paths from the source of gas pressure communicate the gas pressure to the needle and to the medication in order to accomplish these steps. In one embodiment, a valve is positioned to open and close the flow of the pressurized gas to the needle and the flow of the medication to the needle, so that the valve can be operated to deploy the needle and deliver the medication through the needle when the user is ready for the injection. The valve can also be operated to retract the needle when the dose is complete.

Claims

1. A medication delivery device for injection of a medication, comprising:

a medication reservoir;

a pressure housing;

a piston assembly comprising a piston coupled to a needle, the piston being movable from a retracted position to a deployed position; and

a valve fluidically coupled between the medication reservoir and the needle and between the pressure housing and the piston assembly,

wherein the valve is movable from a first position in which the pressure housing is fluidically coupled to the piston assembly through a first fluid flow path, to a second position in which the pressure housing is fluidically coupled to the piston assembly through a second fluid flow path.

2. The medication delivery device of claim 1, wherein the first fluid flow path is fluidically coupled to a first side of the piston, and the second fluid flow path is fluidically coupled to a second side of the piston that is opposite the first side.

3. The medication delivery device of claim 2, wherein the first side of the piston comprises a downwardly facing surface, and the second side of the piston comprises an upwardly facing surface.

4. The medication delivery device of claim 3, wherein the piston comprises a plate having the upwardly and downwardly facing surfaces, and wherein the plate is slidable within a piston housing to move the piston from the retracted position to the deployed position.

5. The medication delivery device of claim 1, further comprising a third fluid flow path from the pressure housing to the medication reservoir.

6. The medication delivery device of claim 5, further comprising a medication flow path from the medication reservoir to the needle.

7. The medication delivery device of claim 6, wherein the valve comprises a seal that is positioned to block the medication flow path when the valve is in the first position and a passage that is positioned to align with the medication flow path when the valve is in the second position.

8. The medication delivery device of claim 6, further comprising a first vent path fluidically coupling the piston assembly to a first vent port and a second vent path fluidically coupling the piston assembly to a second vent port.

9. The medication delivery device of claim 8, wherein the valve comprises a first indentation that aligns with the first vent path in the first position of the valve and aligns with the second flow path in the second position of the valve, and wherein the valve comprises a second indentation that aligns with the first flow path in the first position of the valve and aligns with the second vent path in the second position of the valve.

10. The medication delivery device of claim 9, wherein the valve further comprises a second seal that is positioned to block the first vent path in the second position of the valve, and a third seal that is positioned to block the second flow path in the first position of the valve and is positioned to block the first flow path in the second position of the valve, and a fourth seal that is positioned to block the second vent path in the first position of the valve.

11. A medication delivery device for injection of a medication, comprising:

a medication reservoir;

a pressure housing containing a source of gas pressure;

a piston assembly comprising a piston coupled to a needle, the piston being movable from a retracted position to a deployed position;

a first flow path from the pressure housing to the piston assembly;

a medication flow path from the medication reservoir to the needle; and

a valve fluidically coupled between the pressure housing and the piston assembly, the valve being movable from a first position in which the valve blocks a flow of the gas pressure through the first flow path, to a second position in which the valve allows such flow to move the piston assembly from the retracted position to the deployed position, and wherein the valve comprises a seal that blocks the medication flow path in the first position of the valve, and wherein the valve comprises a passage that aligns with the medication flow path in the second position of the valve.

12. The medication delivery device of claim 11, further comprising a second flow path from the pressure housing to the piston assembly, wherein in the first position the valve allows a flow of the gas pressure through the second flow path to move the piston assembly to the retracted position, and in the second position the valve blocks such flow through the second flow path.

13. The medication delivery device of claim 12, wherein the first flow path is fluidically coupled to an upwardly facing surface of the piston assembly, and wherein the second flow path is fluidically coupled to a downwardly facing surface of the piston assembly.

14. The medication delivery device of claim 12, further comprising a third pressure flow path from the pressure housing to the medication reservoir.

15. The medication delivery device of claim 11, further comprising an activation button attached to the pressure housing for releasing the gas pressure from the pressure housing.

16. A medication delivery device for injection of a medication, comprising:

a medication reservoir;

a source of gas pressure;

a piston assembly comprising a piston coupled to a needle;

a valve configured to regulate a first fluid flow path from the source of gas pressure to the medication reservoir, and a second fluid flow path from the source of gas pressure to the piston assembly;

wherein the needle is fluidically coupled to the medication reservoir by the valve, and

wherein the piston is movable, by a fluid flow from the source of gas pressure, from a retracted position in which the needle is contained within the medication delivery device to a deployed position in which the needle extends from the medication delivery device, and is movable, by the fluid flow from the source of gas pressure, from the deployed position to the retracted position.

17. The medication delivery device of claim 16, further comprising a valve fluidically coupled between the source of gas pressure and the piston assembly, the valve being movable from a first position in which the valve fluidically connects the fluid flow from the source of gas pressure to a first side of the piston to move the piston to the retracted position, to a second position in which the valve fluidically connects the fluid flow from the source of gas pressure to a second opposite side of the piston to move the piston from the retracted position to the deployed position, and back to the first position to move the piston from the deployed position to the retracted position.

18. The medication delivery device of claim 17, wherein the valve comprises a spool valve having a plurality of passages and a plurality of seals for allowing and blocking the fluid flow from the source of gas pressure.

19. A method for injecting medication, comprising:

providing a medication delivery device comprising;

a medication reservoir containing a medication;

a pressure housing containing a source of gas pressure;

a piston assembly comprising a piston coupled to a needle, the piston being movable from a retracted position in which the needle is contained within the medication delivery device to a deployed position in which the needle extends from the medication delivery device; and

a valve fluidly coupled between the medication reservoir and the needle and between the pressure housing and the piston assembly;

deploying the needle by communicating a fluid flow from the source of gas pressure to the piston assembly;

delivering the medication to the needle by communicating the fluid flow from the source of gas pressure to the medication reservoir; and

retracting the needle by communicating the fluid flow from the source of gas pressure to the piston assembly.

20. The method of claim 19, wherein deploying the needle comprises communicating the fluid flow from the source of gas pressure to an upwardly facing surface of the piston, and wherein retracting the needle comprises communicating the fluid flow from the source of gas pressure to an opposite, downwardly facing surface of the piston.