In vitro analyte sensor, and methods
First Claim
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1. A method of determining the concentration of an analyte in a sample in biological fluid, the method comprising:
- contacting a sample of biological fluid with a sample chamber of an analyte sensor, the sample chamber having a volume;
filling only a portion of the sample chamber with the sample;
monitoring a change in an existing signal from an indicator electrode present in the sample chamber;
determining that the existing signal has not changed during a pre-determined time period; and
determining the analyte concentration in the sample.
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Abstract
In vitro electrochemical sensor that provide accurate and repeatable analysis of a sample of biological fluid are provided. In some embodiments, the sensors have a measurement zone that has a volume less than the volume of the sample chamber. The measurement zone could have a volume of no more than about 0.2 μL.
31 Citations
20 Claims
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1. A method of determining the concentration of an analyte in a sample in biological fluid, the method comprising:
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contacting a sample of biological fluid with a sample chamber of an analyte sensor, the sample chamber having a volume; filling only a portion of the sample chamber with the sample; monitoring a change in an existing signal from an indicator electrode present in the sample chamber; determining that the existing signal has not changed during a pre-determined time period; and determining the analyte concentration in the sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification