Device for rechanneling a cavity, organ path or vessel

• US 8,568,465 B2
• Filed: 03/11/2005
• Issued: 10/29/2013
• Est. Priority Date: 03/11/2004
• Status: Expired due to Fees

• Current Assignee: Pfm Medical AG
• Original Assignee: Pfm Medical AG
• Inventors: Freudenthal, Franz, Schmitz-Rode, Thomas
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): EVERAGE, KEVIN D
• Application Number:
  US10/592,411
• Publication Number:
  US 20070203559A1
• Time in Patent Office: 3,154 Days
• Field of Search: 623 111- 115, 623 118- 121, 623 13- 131, 606/200
• US Class Current: 623/1.11
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61F 2/01 Filters implantable into blood vessels
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2002/9511 the retaining means being filaments or wires
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body

Abstract

In a device (1) for recanalizing a cavity, organ path or vessel (4) which is at least partially occluded by at least one compressible occlusive object, in particular a thrombus or embolus (3), in the body of a human or animal, using at least one compressible and self-expanding stent (10) having a distal (12) and a proximal end (11), the at least one stent (10) is embodied substantially in a bell shape with a widened distal end (12) and a constricted proximal end (11).

Claims

1. A device for rechanneling a cavity, organ, path, or vessel which is at least partially occluded by at least one compressible occlusive object, such as a thrombus or embolus, in the body of a human or animal, comprising:

at least one compressible and self-expanding stent having a reticular structure, said stent having a compressed configuration adapted for positioning within a lumen, and having an expanded configuration;

said stent having a hollow substantially cylindrical body defined by a sidewall;

said stent having a distal end, and having a proximal end in an engagement with said lumen as a means to maintain a connection with said lumen during insertion into said body and until removal thereof from said body,

said sidewall at said proximal end of said stent in said expanded configuration having an outward taper from a narrowest diameter adjacent to engagement with said lumen, to a wider second diameter at a widened proximal portion of said sidewall;

said sidewall at said distal end having an inward taper from a larger diameter distal end for a distance toward said widened proximal portion;

said inward taper defining a recess in said sidewall, said recess having a smaller diameter than said distal end and said widened proximal portion;

said stent sidewall formed entirely in a reticular structure having a multiplicity of openings therein, said stent in said expanded configuration sized to exert and expanding force to opposing sides of a cavity, organ, path, or vessel in which it is situated in an as-used position;

said openings configured with an opening width which is smaller than the dimensions of the occlusive object to be compressed;

said openings providing means for maintaining substantially full fluid flow through all areas of said sidewall thereby minimizing any impedance of fluid flow therethrough;

said recess providing means for an entrapment of said occlusive object and a concurrent compression of said occlusive object, when said stent is in said expanded configuration in said as-used position in between said occlusive object and a said opposing side surface of said cavity, organ path or vessel;

said entrapment providing means for prevention of a repositioning of said occlusive object within said cavity, organ, path, or vessel; and

said fluid flow through said openings providing means for a fluid rechanneling through said stent sidewall in said as-used position;

wherein;

said stent is deliverable with a catheter and said device further comprises a suction device operable to suction off solid constituents of the occlusive object to be compressed or parts of the object at subatmospheric pressure, the suction device comprising a cannula or tubular device that is positionable adjacent to the stent when the stent is deployed in said cavity, organ, path or vessel;

said device further comprises an attachment to said stent, said attachment formed from one or more wire-like attachment elements comprising single wires or a stranded wire;

a proximal end of said stent is formed of a plurality of partly twisted loops that are passed out of said reticular structure of said stent, said partly twisted loops comprising at least one relatively long partly twisted loop and at least one relatively short partly twisted loop, wherein said at least one relatively long partly twisted loop is threaded through said at least one relatively short partly twisted loop to form one or more wire-like attachment elements for said stent; and

at least one of the partly twisted loops is held together by said one or more wire-like attachment elements.

2. The device as claimed in claim 1, further comprising a sleeve engaged at said proximal end.

3. The device as claimed in claim 1, wherein substantially all said stent sidewall is made of a braided material, woven material, scrim, or a combination thereof.

4. The device of claim 3, wherein substantially all of said stent sidewall is made of a wire braid, a woven wire material, a wire scrim, or a combination thereof.

5. The device as claimed in claim 1, wherein the stent consists of a tube which is slotted at least along part of its length.

6. The device as claimed in claim 1, wherein the stent is formed of a material having a biocompatible surface coating selected from the group consisting of heparin, a carbonization of nitinol, a nanotechnological coating, radiopaque particles, a coating releasing an active substance, a microporous coating, and a biotechnological coating.

7. The device as claimed in claim 1, wherein the stent is formed of a biocompatible material selected from the group consisting of metal, metal alloy, plastic, and combinations thereof.

8. The device as claimed in claim 7, wherein said stent comprises stainless steel, nitinol, or a combination thereof.

9. The device as claimed in claim 1, wherein at least one of said diameter of said distal end and said second diameter is substantially equal to or slightly larger than the diameter of the cavity, organ path or vessel to be rechanneled.

10. The device as claimed in claim 1, wherein at least one of the partly twisted loops is configured to form a wire-like attachment element that is closed at its end.

11. The device as claimed in claim 10, wherein the at least one of said partly twisted loops comprises a twisted section and a section threaded through at least one adjacent partly twisted loop, and includes a sleeve element in a region between the twisted section and the section threaded through the at least one adjacent partly twisted loop.

12. The use of the device as claimed in claim 1 as an aortic filter.

13. The use as claimed in claim 12, and configuring the device substantially to have the same length as an aortic arch in which it is disposed, for the protection of carotid artery and coronary arteries.

14. The use as claimed in claim 12, wherein the device is configured to be shorter than an aortic arch in which it is disposed and has an end which is slightly widened or not widened at all, for the protection of both carotid arteries.