System and methods for neurologic monitoring and improving classification and treatment of neurologic states

• US 8,577,451 B2
• Filed: 12/16/2009
• Issued: 11/05/2013
• Est. Priority Date: 12/16/2009
• Status: Active Grant

• Current Assignee: Brainscope SPV LLC
• Original Assignee: Brainscope Company Inc.
• Inventors: Causevic, Elvir
• Primary Examiner(s): Natnithithadha, Navin
• Assistant Examiner(s): BERHANU, ETSUB D
• Application Number:
  US12/639,218
• Publication Number:
  US 20110144519A1
• Time in Patent Office: 1,420 Days
• Field of Search: 600/544
• US Class Current: 600/544
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/4064 Evaluating the brain A61B5/031, A61B5/369, A61B5/14553 take precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: A61B 5/726 using Wavelet transforms
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

Methods and systems for assessing brain activity and collecting information related to a patient'"'"'s condition and brain electrical activity are provided.

Claims

1. A method for monitoring or evaluating a neurologic state of a patient, comprising:

collecting data related to brain electrical activity of the patient at a first location using at least one electrode;

transferring the data related to brain electrical activity to a memory unit located at a second location that is different from the first location;

providing a processor configured to classify the neurological state of the patient based on the data related to brain electrical activity and data stored in a database;

receiving data related to non-electrical diagnostic information related to the neurological state of the patient based on at least one evaluation technique;

updating the database to include the data related to brain electrical activity and the non-electrical diagnostic information related to the neurological state; and

correlating the data related to brain electrical activity and the data related to non-electrical diagnostic information to allow development of one or more diagnostic and treatment algorithm.

2. The method of claim 1, further including repeating the method with at least one additional patient using the updated database to classify the neurological state of the additional patient.

3. The method of claim 1, further including repeating the method, wherein collecting data related to brain electrical activity is performed with two or more patients at at least two or more different locations.

4. The method of claim 1, further including, upon classifying the neurological state, notifying a predetermined person that a classification has been provided so that the predetermined person can evaluate the patient and provide information related to the neurological state of the patient based on at least one evaluation technique not including brain electrical activity data.

5. The method of claim 1, wherein the classification includes at least one of a psychiatric disorder, an organic neurological disorder, a structural neurological disorder, a metabolic disorder, an intoxicated state, and a normal state.

6. The method of claim 1, wherein the classification includes at least one of an ischemic brain state and a hemorrhagic state.

7. The method of claim 1, wherein the classification includes an abnormal intracranial pressure.

8. The method of claim 1, further including providing a treatment recommendation based on data stored in the database and the classification of the neurologic state of the patient.

9. A method for monitoring or evaluating a neurologic state of a patient, comprising:

collecting data related to brain electrical activity of a patient at a first location using at least one electrode;

transferring the data related to brain electrical activity to a memory unit located at a second location that is different from the first location;

classifying, using a processor, the neurological state of the patient based on the data related to brain electrical activity and data stored in a first database;

providing an assessment of the neurological state of the patient based on data related to non-electrical diagnostic information about the patient;

correlating a result of the classification with the assessment based on the data related to non-electrical diagnostic information;

updating the first database to include the data related to brain electrical activity; and

updating a second database containing longitudinal data related to the patient'"'"'s a neurologic state at multiple time points.

10. The method of claim 9, further including collecting data related to brain electrical activity of the patient at a later time;

and

comparing the data related to brain electrical activity of the patient at the later time to data stored in the second database to determine a change in the patient'"'"'s neurologic state.

11. The method of claim 9, further including providing a treatment recommendation based on data stored in the database and the classification of the neurologic state of the patient.

12. The method of claim 11, further including evaluating the response of a patient to a treatment and providing a subsequent treatment recommendation based on data stored in the database, the classification of the neurologic state of the patient, and the patient'"'"'s response to the treatment.

13. The method of claim 9, wherein providing a classification includes identifying at least one similarity between the brain electrical activity data of the patient and brain electrical activity data stored in the first database for at least one additional patient having a known neurological state and assigning the known neurological state to the patient.

14. The method of claim 13, wherein the at least one additional patient includes a group of patients.