Systems and methods for determining cardiac output using pulmonary artery pressure measurements
First Claim
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1. A method of determining cardiac output within a patient'"'"'s heart, the method comprising:
- sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery of the patient in order to sense the arterial pressure waveform on a right side of the patient'"'"'s heart;
identifying the systolic portion of the arterial pressure waveform sensed by the pressure sensor;
identifying the beginning of a cardiac cycle and correlating the systolic portion of the arterial pressure waveform with the beginning of the cardiac cycle;
identifying an estimate of the valve closure time of the pulmonary valve using the arterial pressure waveform, wherein identifying the estimate of the valve closure time of the pulmonary valve includes;
determining a first point, the first point comprising a positive-going zero of a second derivative of the arterial pressure waveform;
determining a second point, the second point comprising a point of maximum positive value of the second derivative of the arterial pressure waveform; and
determining a midpoint in time between the first point and the second point, wherein the midpoint provides the estimate of the valve closure time of the pulmonary valve;
estimating the stroke volume using the systolic portion of the arterial pressure waveform and the estimate of the pulmonary valve closure time; and
obtaining a measure of cardiac output based at least in part on the estimated stroke volume.
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Abstract
Systems and methods for determining cardiac output are disclosed. An illustrative method of determining cardiac output includes sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery, identifying a valve closure time associated with the pulmonary valve using the sensed arterial pressure waveform, estimating stroke volume using the systolic portion of the arterial pressure waveform and the valve closure time, and obtaining a measure of cardiac output based on the estimated stroke volume.
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18 Claims
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1. A method of determining cardiac output within a patient'"'"'s heart, the method comprising:
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sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery of the patient in order to sense the arterial pressure waveform on a right side of the patient'"'"'s heart; identifying the systolic portion of the arterial pressure waveform sensed by the pressure sensor; identifying the beginning of a cardiac cycle and correlating the systolic portion of the arterial pressure waveform with the beginning of the cardiac cycle; identifying an estimate of the valve closure time of the pulmonary valve using the arterial pressure waveform, wherein identifying the estimate of the valve closure time of the pulmonary valve includes; determining a first point, the first point comprising a positive-going zero of a second derivative of the arterial pressure waveform; determining a second point, the second point comprising a point of maximum positive value of the second derivative of the arterial pressure waveform; and determining a midpoint in time between the first point and the second point, wherein the midpoint provides the estimate of the valve closure time of the pulmonary valve; estimating the stroke volume using the systolic portion of the arterial pressure waveform and the estimate of the pulmonary valve closure time; and obtaining a measure of cardiac output based at least in part on the estimated stroke volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of determining one or more hemodynamic parameters associated with the operation of a patient'"'"'s heart, the method comprising:
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sensing an arterial pressure waveform using a pressure sensor located within a pulmonary artery of the patient in order to sense the arterial pressure waveform on a right side of the patient'"'"'s heart; identifying the beginning of a cardiac cycle and correlating the arterial pressure waveform sensed by the pressure sensor with the beginning of the cardiac cycle; identifying an estimate of the valve closure time of the pulmonary valve using the arterial pressure waveform, wherein identifying the estimate of the valve closure time of the pulmonary valve includes; determining a first point, the first point comprising a positive-going zero of a second derivative of the arterial pressure waveform; determining a second point, the second point comprising a point of maximum positive value of the second derivative of the arterial pressure waveform; and determining a midpoint in time between the first point and the second point, wherein the midpoint provides the estimate of the valve closure time of the pulmonary valve; and obtaining at least one hemodynamic parameter associated with the patient'"'"'s heart based at least in part on the estimate of the valve closure time.
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14. A system for determining cardiac output within a patient'"'"'s heart, the system comprising:
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a pressure sensor located within a pulmonary artery of the patient, the pressure sensor adapted to sense right side arterial blood pressure within the artery and transmit an arterial pressure waveform signal; a monitoring device in communication with the pressure sensor, the monitoring device including a processor adapted to determine cardiac output based at least in part on the arterial pressure waveform signal; and wherein the processor is adapted to determine cardiac output based at least in part on a valve closure time associated with the pulmonary valve, wherein the processor is further adapted to determine an estimate of the valve closure time of the pulmonary valve by; determining a first point, the first point comprising a positive-going zero of a second derivative of the arterial pressure waveform; determining a second point, the second point comprising a point of maximum positive value of the second derivative of the arterial pressure waveform; and determining a midpoint in time between the first point and the second point, wherein the midpoint provides the estimate of the valve closure time of the pulmonary valve. - View Dependent Claims (15, 16, 17, 18)
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Specification