Enhanced erythropoiesis and iron metabolism
DCFirst Claim
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1. A method for decreasing hepcidin expression in a subject in need thereof, the method comprising administering to the subject an effective amount of a heterocyclic carboxamide compound that stabilizes the alpha subunit of hypoxia-inducible factor (HIFα
- ), thereby decreasing hepcidin expression in the subject.
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Abstract
The present invention relates to methods and compounds for decreasing the expression of hepcidin, a protein associated with regulation of iron metabolism.
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9 Claims
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1. A method for decreasing hepcidin expression in a subject in need thereof, the method comprising administering to the subject an effective amount of a heterocyclic carboxamide compound that stabilizes the alpha subunit of hypoxia-inducible factor (HIFα
- ), thereby decreasing hepcidin expression in the subject.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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