Pirfenidone treatment for patients with atypical liver function

  • US 8,609,701 B2
  • Filed: 11/09/2009
  • Issued: 12/17/2013
  • Est. Priority Date: 11/10/2008
  • Status: Active Grant
First Claim
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1. A method of treating a patient in need of pirfenidone and suffering from a Grade 2 abnormality in a liver function biomarker selected from the group consisting of alanine transaminase (ALT) and aspartate transaminase (AST) and wherein the abnormality occurs after a first pirfenidone administration, comprising providing to said patient a second administration of pirfenidone, comprising (a) administering to said patient at doses of at least 1600 mg/day or 1602 mg/day.

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