Assembly for placing a prosthetic valve in a duct in the body

• US 8,628,570 B2
• Filed: 08/18/2011
• Issued: 01/14/2014
• Est. Priority Date: 07/04/2001
• Status: Expired due to Fees

• Current Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: Seguin, Jacques
• Primary Examiner(s): GHERBI, SUZETTE JAIME J
• Application Number:
  US13/212,227
• Publication Number:
  US 20110301692A1
• Time in Patent Office: 880 Days
• Field of Search: 623/1.24, 623 21- 219
• US Class Current: 623/2.17
• CPC Class Codes: A61F 2/2403 with pivoting rigid closure members check valves with hinged closure members in general F16K15/03
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/006 modular

Abstract

A prosthetic valve assembly can include a radially expandable stent. The stent can include a first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen. The stent can also include a plurality of rods extending between the first annular portion and the second annular portion. The prosthetic valve assembly can further include an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion. The prosthetic valve assembly is configured to be delivered by catheterization.

Claims

1. A prosthetic valve assembly comprising:

a radially expandable stent having

a first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, the first expandable annular portion comprising a peripheral protrusion surrounding a distal end of the first expandable annular portion that is configured to form a seal with a wall of a body lumen;

a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, and

a plurality of rods extending between the first annular portion and the second annular portion; and

an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion,

wherein the plurality of rods includes at least one rod having a first portion that contacts the valve and a second portion that does not contact the valve,

wherein the prosthetic valve assembly is configured to be delivered by catheterization.

2. The prosthetic valve assembly of claim 1, wherein the implantable prosthetic valve comprises at least two commissures, and wherein each commissure of the at least two commissures is aligned with a respective rod of the plurality of rods.

3. The prosthetic valve assembly of claim 1, wherein the plurality of rods are uniformly spaced apart around a periphery of the prosthetic valve assembly.

4. The prosthetic valve assembly of claim 1, wherein the plurality of rods each have a length such that the first expandable annular portion, in its expanded state, bears against a native valvular ring of an aortic valve and such that the second expandable annular portion, in its expanded state, bears against a portion of a wall of an aorta beyond the coronary ostia.

5. The prosthetic valve assembly of claim 4, wherein the radially expandable stent is configured to not obstruct the coronary ostia.

6. The prosthetic valve assembly of claim 1, wherein the stent further comprises a frustoconical portion extending from a proximal end of the first expandable annular portion.

7. The prosthetic valve assembly of claim 6, wherein the frustoconical portion is configured, in an expanded state, to bear against a wall of a ventricle of a heart.

8. The prosthetic valve assembly of claim 1, wherein the first and second expandable annular portions are each configured to be balloon expandable.

9. The prosthetic valve assembly of claim 1, wherein the first and second expandable annular portions each configured to be self expandable.

10. The prosthetic valve assembly of claim 1, wherein the second expandable annular portion is configured, in its expanded state, to have a larger diameter than a diameter of the first expandable annular portion in its expanded state.

11. The prosthetic valve assembly of claim 1, wherein the valve is mounted to a portion of the radially expandable stent that does not bear against a wall of a native body lumen.

12. The prosthetic valve assembly of claim 1, wherein the first expandable annular portion comprises a network of filaments.

13. The prosthetic valve assembly of claim 12, wherein the network of filaments form a mesh.

14. The prosthetic valve assembly of claim 1, wherein the second expandable annular portion comprises a network of filaments.

15. The prosthetic valve assembly of claim 14, wherein the network of filaments form a mesh.

16. The prosthetic valve assembly of claim, wherein the stent is configured such that the seal formed by the peripheral protrusion is distal to a native valvular ring of an aortic valve upon implantation.

17. A prosthetic valve assembly comprising:

a radially expandable stent having

a first expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, the first expandable annular portion comprising a peripheral protrusion surrounding a distal end of the first expandable annular portion that is configured to form a seal with a wall of a body lumen;

a second expandable annular portion that is configured, in an expanded state, to bear against a wall of a native body lumen, and

a plurality of rods extending between the first annular portion and the second annular portion; and

an implantable prosthetic valve mounted to the stent such that the valve is between the first annular portion and the second annular portion,

wherein the plurality of rods includes at least one rod that has a portion that is radially outside the valve,

wherein the prosthetic valve assembly is configured to be delivered by catheterization.

18. The prosthetic valve assembly of claim 17, wherein the implantable prosthetic valve comprises at least two commissures, and wherein each commissure of the at least two commissures is aligned with a respective rod of the plurality of rods.

19. The prosthetic valve assembly of claim 17, wherein the plurality of rods are uniformly spaced apart around a periphery of the prosthetic valve assembly.

20. The prosthetic valve assembly of claim 17, wherein the plurality of rods each have a length such that the first expandable annular portion, in its expanded state, bears against a native valvular ring of an aortic valve and such that the second expandable annular portion, in its expanded state, bears against a portion of a wall of an aorta beyond the coronary ostia.

21. The prosthetic valve assembly of claim 17, wherein the radially expandable stent is configured to not obstruct the coronary ostia.

22. The prosthetic valve assembly of claim 17, wherein the first and second expandable annular portions are each configured to be balloon expandable.

23. The prosthetic valve assembly of claim 17, wherein the first and second expandable annular portions each configured to be self expandable.

24. The prosthetic valve assembly of claim 17, wherein the second expandable annular portion is configured, in its expanded state, to have a larger diameter than a diameter of the first expandable annular portion in its expanded state.

25. The prosthetic valve assembly of claim 17, wherein the valve is mounted to a portion of the radially expandable stent that does not bear against a wall of a native body lumen.

26. The prosthetic valve assembly of claim 17, wherein the first expandable annular portion and the second expandable annular portion each comprise a network of filaments.

27. The prosthetic valve assembly of claim 17, wherein the stent is configured such that the seal formed by the peripheral protrusion is distal to a native valvular ring of an aortic valve upon implantation.