Methods and devices for providing prolonged drug therapy

  • US 8,629,179 B2
  • Filed: 10/19/2009
  • Issued: 01/14/2014
  • Est. Priority Date: 11/12/1996
  • Status: Expired due to Term
First Claim
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1. A tablet oral dosage form for effectively treating Attention Deficit Disorder or Attention Deficit Hyperactivity Disorder in a subject comprising:

  • an immediate release portion comprising methylphenidate or a pharmaceutically effective salt thereof; and

    a sustained release portion comprising methylphenidate or a pharmaceutically effective salt thereof and a pharmaceutically acceptable carrier,wherein;

    said dosage form releases said methylphenidate over a period comprising first, second, third, fourth, fifth, and sixth sequential one-hour time intervals, andsaid sustained release portion releases more of said methylphenidate during said second interval than during said first interval, more of said methylphenidate during said third interval than during said second interval, and more of said methylphenidate during said fourth interval than during said third interval.

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