Devices, systems, and methods for mapping organ profiles
First Claim
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1. A system comprising:
- a device having a proximal end and a distal end, the distal end of the device configured for placement into a body lumen, the device comprising a first electrode located between the proximal and distal ends of the device; and
a processor operably connected to the first electrode of the device, the processor operable to collect conductance data from the device to determine a profile of the body lumen based upon the conductance data, the conductance data collected at a plurality of locations within the body lumen and determined at each of the plurality of locations when the first electrode is immersed in a fluid within the body lumen;
wherein the processor further comprises a computational program configured to detect a bifurcation in the body lumen based upon the conductance data obtained at the plurality of locations and changes in cross-sectional area identified using the conductance data, the conductance data including data obtained at the bifurcation using the device, and distinguishing the bifurcation from a lesion.
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Abstract
Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify and locate lesions and/or anatomical structures within a lumen and accurately place leads and/or devices within a lumen, through determining the intralumen conductance and/or cross-sectional area at a plurality of locations within the body lumen.
38 Citations
20 Claims
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1. A system comprising:
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a device having a proximal end and a distal end, the distal end of the device configured for placement into a body lumen, the device comprising a first electrode located between the proximal and distal ends of the device; and a processor operably connected to the first electrode of the device, the processor operable to collect conductance data from the device to determine a profile of the body lumen based upon the conductance data, the conductance data collected at a plurality of locations within the body lumen and determined at each of the plurality of locations when the first electrode is immersed in a fluid within the body lumen; wherein the processor further comprises a computational program configured to detect a bifurcation in the body lumen based upon the conductance data obtained at the plurality of locations and changes in cross-sectional area identified using the conductance data, the conductance data including data obtained at the bifurcation using the device, and distinguishing the bifurcation from a lesion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A system comprising:
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a catheter having a proximal end and a distal end, the distal end of the catheter configured for placement into a body lumen, the catheter comprising a first electrode and a second electrode located between the proximal and distal ends of the catheter, the catheter further comprising a passageway configured for passing fluid through the catheter to a location of the first and second electrodes, such that fluid passing through the passageway comes in contact with the first and second electrodes; and a processor operably connected to the first and second electrodes of the catheter, the processor operable to collect conductance data from the device to determine a profile of the body lumen based upon the conductance data, the conductance data collected at a plurality of locations within the body lumen and determined at each of the plurality of locations when the first and second electrodes are immersed in a fluid within the body lumen, the processor further configured to calculate a cross-sectional area of the body lumen at each of the plurality of locations within the body lumen using the conductance data; wherein the processor further comprises a computational program configured to detect a bifurcation in the body lumen based upon the conductance data obtained at the plurality of locations and changes in cross-sectional area identified using the conductance data, the conductance data including data obtained at the bifurcation using the device, and distinguishing the bifurcation from a lesion; wherein the fluid within the body lumen comprises a first fluid having a first conductivity and a second fluid having a second conductivity; and wherein the conductance data is determined at each of the plurality of locations when the first and second electrodes are immersed in each of the first fluid and the second fluid. - View Dependent Claims (16, 17, 18, 19)
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20. A system comprising:
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a device having a proximal end and a distal end, the distal end of the device configured for placement into a body lumen, the device comprising a first electrode and a second electrode located between the proximal and distal ends of the device; and a processor operably connected to the first and second electrodes of the device, the processor operable to collect conductance data from the device to determine a profile of the body lumen based upon the conductance data, the conductance data collected at a plurality of locations within the body lumen and determined at each of the plurality of locations when the first and second electrodes are immersed in a fluid within the body lumen, the processor further configured to calculate a cross-sectional area of the body lumen at each of the plurality of locations within the body lumen using the conductance data; wherein the processor further comprises a computational program configured to detect a bifurcation in the body lumen based upon the conductance data obtained at the plurality of locations and changes in cross-sectional area identified using the conductance data, the conductance data including data obtained at the bifurcation using the device, and distinguishing the bifurcation from a lesion, the computational program further configured to adjust the conductance data to eliminate a conductance spike due to the detection of a bifurcation; wherein the fluid within the body lumen comprises a first fluid having a first conductivity and a second fluid having a second conductivity; wherein the conductance data comprises a first conductance value determined at each of the plurality of locations when the first and second electrodes are immersed in the first fluid and a second conductance value determined at each of the plurality of locations when the first and second electrodes are immersed in the second fluid; and wherein the profile of the body lumen is determined from the first and second conductance values collected from each of the plurality of locations, the first conductivity of the first fluid, and the second conductivity of the second fluid.
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Specification