Seizure detection using coordinate data

• US 8,641,646 B2
• Filed: 07/30/2010
• Issued: 02/04/2014
• Est. Priority Date: 07/30/2010
• Status: Active Grant

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Colborn, John C.
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US12/847,922
• Publication Number:
  US 20120029390A1
• Time in Patent Office: 1,285 Days
• Field of Search: 600/544, 600/545, 600/595
• US Class Current: 600/595
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/0245 by using sensing means generating electric signals, i.e. ECG signals
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/1112 Global tracking of patients, e.g. by using GPS
• CPC Class Codes: A61B 5/1116 Determining posture transitions
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/4094 Diagnosing or monitoring seizure diseases, e.g. epilepsy
• CPC Class Codes: A61B 5/4836 Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6847 mounted on an invasive device
• CPC Class Codes: A61N 1/36064 Epilepsy
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/36139 with automatic adjustment
• CPC Class Codes: A61N 1/37252 Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
• CPC Class Codes: A61N 1/37282 characterised by communication with experts in remote locations using a network
• CPC Class Codes: G16H 20/30 relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 20/40 relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 40/67 : for remote operation
• CPC Class Codes: G16H 50/20 : for computer-aided diagnosis, e.g. based on medical expert systems

Abstract

A seizure detection device includes a coordinate data interface configured to receive coordinate data for a human, a memory to store coordinate data for a defined location of the human, and a seizure detector configured to identify a seizure event responsive to the coordinate data.

Claims

1. A seizure detection device comprising:

a coordinate data interface configured to receive coordinate data indicating a coordinate location of a patient;

a memory configured to store the coordinate data associated with a defined location; and

a seizure detector configured to detect a seizure event in the patient based on the coordinate data and body parameter data corresponding to at least one body parameter.

2. The seizure detection device of claim 1, wherein the coordinate data includes global positioning system data obtained from a global positioning system, local coordinate data obtained from a local coordinate system, or both.

3. The seizure detection device of claim 2, wherein the coordinate data includes time data, and wherein the global positioning system data, the local coordinate data, or both, includes velocity data, acceleration data, or both.

4. The seizure detection device of claim 1, further comprising a motion detector configured to detect motion of the patient, wherein the seizure detector is responsive to the coordinate data and the motion of the patient.

5. The seizure detection device of claim 4, wherein the motion detector comprises an accelerometer.

6. The seizure detection device of claim 1, wherein the seizure detector is further configured to:

dynamically determine a seizure detection threshold based at least in part on the coordinate data; and

compare the body parameter data to the seizure detection threshold.

7. The seizure detection device of claim 1, further comprising a communication interface configured to communicate with an external communication device:

the body parameter data, seizure event data, seizure detection threshold data, the coordinate data, or a combination thereof.

8. The seizure detection device of claim 1, wherein the coordinate data includes altitude data.

9. The seizure detection device of claim 1, further comprising a movement calculator configured to determine an amount of movement of the patient responsive to the coordinate data.

10. The seizure detection device of claim 1, wherein the body parameter data is determined based on a cardiovascular signal, a respiratory signal, a skin signal, a pupillary signal, a temperature signal, a peristaltic signal, a brain signal, a cranial nerve signal, a spinal cord signal, a peripheral nerve signal, an autonomic nerve signal, an autonomic ganglia signal, a biomedical presence signal, a biomedical concentration signal, a body kinetic signal, a body position signal, a body force signal, or a combination of two or more thereof.

11. The seizure detection device of claim 7, wherein the external communication device activates an implantable medical device based at least in part on the body parameter data, the coordinate data, or both.

12. The seizure detection device of claim 11, wherein the implantable medical device includes a pulse generation device for nerve stimulation to the patient.

13. A method comprising:

receiving coordinate data indicating a coordinate location of a patient;

determining a seizure threshold based at least in part on the coordinate data; and

detecting a seizure event in the patient based at least in part on the seizure threshold.

14. The method of claim 13, wherein receiving the coordinate data includes receiving global positioning system data from a global positioning system, receiving local coordinate system data from a local coordinate system, or both.

15. The method of claim 14, wherein receiving the coordinate data includes receiving time data, and wherein receiving the global positioning system data, the local coordinate system data, or both, includes receiving velocity data, acceleration data, or both.

16. The method of claim 13, further comprising determining an amount of movement of the patient based on the coordinate data, wherein the seizure event is detected in the patient based on the coordinate data and the amount of movement of the patient.

17. The method of claim 13, further comprising logging seizure event data associated with the coordinate data.

18. The method of claim 13, further comprising sending seizure event data associated with the coordinate data to an external communication device.

19. The method of claim 13, further comprising receiving input data indicating an activity being performed by the patient, wherein the seizure threshold is determined based on the input data.

20. The method of claim 19, wherein the input data further indicates a location where the activity is being performed.