Solid formulations of ospemifene

  • US 8,642,079 B2
  • Filed: 02/23/2004
  • Issued: 02/04/2014
  • Est. Priority Date: 02/23/2004
  • Status: Active Grant
First Claim
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1. A solid drug formulation comprising granulates containing 30 to 90 mg of ospemifene or a pharmaceutically acceptable salt thereof, in combination with one or more intra-granular excipients selected from a disintegrant, a diluent, a binder, and combinations of the same;

  • wherein 90% of the ospemifene or the pharmaceutically acceptable salt thereof has a particle size less than 50 micrometers and 50% of the ospemifene or the pharmaceutically acceptable salt thereof has a particle size less than 15 micrometers.

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