Compositions, methods, and systems for inferring bovine breed
First Claim
1. A method to infer breed of a bovine subject from a nucleic acid sample of the bovine subject, comprising identifying in the nucleic acid sample, at least one nucleotide occurrence of at least one single nucleotide polymorphism (SNP) corresponding to position 300 of any one of SEQ ID NOS:
- 1 to 4868 or SEQ ID NOS;
64887 to 64895, wherein the SNP is associated with a breed, thereby inferring the breed of the bovine subject.
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Abstract
Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.
85 Citations
19 Claims
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1. A method to infer breed of a bovine subject from a nucleic acid sample of the bovine subject, comprising identifying in the nucleic acid sample, at least one nucleotide occurrence of at least one single nucleotide polymorphism (SNP) corresponding to position 300 of any one of SEQ ID NOS:
- 1 to 4868 or SEQ ID NOS;
64887 to 64895, wherein the SNP is associated with a breed, thereby inferring the breed of the bovine subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- 1 to 4868 or SEQ ID NOS;
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13. A method for sorting bovine subjects, comprising:
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a. inferring a breed for a first bovine subject from a nucleic acid sample of the first bovine subject, by a method comprising identifying a nucleotide occurrence of at least one single nucleotide polymorphism (SNP) corresponding to position 300 of at least one of SEQ ID NOS;
1 to 4868 or SEQ ID NOS;
64887 to 64895, wherein the SNP is associated with the breed; andb. sorting the first bovine subject based on the inferred breed, and repeating for additional subjects, thereby sorting bovine subjects. - View Dependent Claims (14)
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15. A method for breeding a bovine subject, comprising:
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a. inferring breed of a bovine candidate for use in breeding programs from a nucleic acid sample of the bovine candidate by a method comprising identifying the nucleotide occurrence of at least one single nucleotide polymorphism (SNP) corresponding to position 300 of at least one of SEQ ID NOS;
1 to 4868 or SEQ ID NOS;
64887 to 64895, wherein the SNP is associated with breed; andb. determining whether to select the individual for use in breeding programs based on the inferred breed, thereby breeding the bovine subject. - View Dependent Claims (16, 17, 18, 19)
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Specification