Methods for treating extreme insulin resistance in patients resistant to previous treatment with other anti-diabetic drugs employing an SGLT2 inhibitor and compositions thereof

  • US 8,685,934 B2
  • Filed: 05/26/2010
  • Issued: 04/01/2014
  • Est. Priority Date: 05/27/2009
  • Status: Active Grant
First Claim
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1. A method for treating extreme insulin resistance in a mammalian patient, wherein the patient has previously been treated with ≧

  • 50 units of insulin per day and at least one or more of metformin, pioglitazone, or rosiglitazone, and wherein the previous treatment provided inadequate glycemic control (HbA1c<

    7%) the method comprising;

    administering to said patient in need of treatment a therapeutically effective amount of an SGLT2 inhibitor of formula;

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