Apparatus and method for stimulating a brain of a person

• US 8,700,167 B2
• Filed: 12/22/2006
• Issued: 04/15/2014
• Est. Priority Date: 12/22/2006
• Status: Active Grant

• Current Assignee: Ebs Technologies Gmbh
• Original Assignee: Ebs Technologies Gmbh
• Inventors: Sabel, Bernhard A.
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): EDWARDS, PHILIP CHARLES
• Application Number:
  US12/520,616
• Publication Number:
  US 20090319004A1
• Time in Patent Office: 2,671 Days
• Field of Search: 607/47, 607/54, 607/53
• US Class Current: 607/54
• CPC Class Codes: A61B 5/245 specially adapted for magnetoencephalographic [MEG] signals
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/372 Analysis of electroencephalograms
• CPC Class Codes: A61H 5/00 Exercisers for the eyes
• CPC Class Codes: A61N 1/326 for promoting growth of cells, e.g. bone cells
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36046 of the eye
• CPC Class Codes: A61N 2/02 using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence

Abstract

An apparatus for stimulating a brain (3B) of a person (2) comprising a detector (10) for detecting an induced or a spontaneous physiological signal generated by the brain (3B), a control unit (12) being connected to said detector (10) for comparing the detected physiological signal with a criterion to determine an optimal setting of a variable signal parameter, a first signal generator (8) for applying an electrical stimulation signal (EES) to said person (2) and/or at least one second signal generator (9) for applying a sensory stimulation signal (SSS) to a sensory organ (3A) of said person (2), wherein a signal parameter of the stimulation signals (ESS, SSS) are adjusted to the determined optimal setting of said signal parameter.

Claims

1. A stimulation apparatus for stimulating a brain of a person comprising:

(i) a first signal generator configured to apply a generated electrical stimulation signal to a sensory organ of said person;

(ii) a second signal generator configured to apply a generated sensory stimulation signal to the sensory organ of said person;

(iii) a signal detector configured to detect an induced brain signal, wherein the induced brain signal is an electro- or magnetoencephalogram signal generated by the brain of said person in response to the applied electrical stimulation signal or in response to the electrical stimulation signal and the sensory stimulation signal; and

(iv) a control unit which is (a) configured to control the first signal generator, (b) configured to control the second signal generator and (c) configured to receive and analyze the induced brain signal from the signal detector,

wherein, in a first operation mode, the control unit is configured to vary a frequency of the applied stimulation signal formed by the electrical stimulation signal or by both, the electrical and the sensory stimulation signal over a predetermined frequency range while analyzing the induced brain signal to determine an optimal setting of the frequency producing a maximum amplitude of the induced brain signal,

wherein, in a second operation mode, the control unit is configured to apply both the electrical stimulation signal and the sensory stimulation signal to the sensory organ with a frequency that is adjusted to the determined optimal setting of the frequency forming an individual resonance frequency of said person,

wherein the control unit further includes a phase control unit, the phase control unit controlling a phase relationship between the sensory stimulation signal generated by the second signal generator and the electrical stimulation signal generated by the first signal generator,

wherein the electrical stimulation signal generated by the first signal generator and the sensory stimulation signal generated by the second signal generator have a predetermined phase relationship,

wherein each of the sensory stimulation signal and the electrical stimulation signal has a frequency associated therewith, and

wherein the frequency of the sensory stimulation signal generated by the second signal generator is equal to the frequency of the electrical stimulation signal generated by the first signal generator.

2. The stimulation apparatus according to claim 1, wherein said signal detector is an EEG-detector.

3. The stimulation apparatus according to claim 2, wherein said sensory stimulation signal is an optical stimulation signal, an auditory stimulation signal, or a vibration stimulation signal.

4. The stimulation apparatus according to claim 3, further comprising a light bulb, wherein the optical sensory stimulation signal is formed by pulsed flash light generated by said light bulb.

5. The stimulation apparatus according to claim 3, further comprising a light emitting diode, wherein the optical sensory stimulation signal is generated by said light emitting diode device.

6. The stimulation apparatus according to claim 3, further comprising a display monitor, wherein the optical sensory stimulation signal is formed by a predetermined stimulus pattern displayed on said display monitor.

7. The stimulation apparatus according to claim 1, wherein said stimulation signal is a sine wave signal or a rectangular signal.

8. The stimulation apparatus according to claim 1, wherein the frequency of the stimulation signal produced by the first signal generator or the second signal generator is varied in a frequency range Δ

f of about 0-100 Hz.

9. The stimulation apparatus according to claim 1, further comprising a memory unit, wherein the determined optimal setting of the frequency of the stimulation signal is stored in said memory unit.

10. The stimulation apparatus according to claim 1, further comprising control lines, wherein said control unit is connected to the signal generators via said control lines to control said signal generators such that the electrical stimulation signal and the sensory stimulation signal comprise a predetermined phase relationship.

11. The stimulation apparatus according to claim 1, further comprising at least one of electrodes and magnetic stimulation coils, wherein the electrical stimulation signal is adapted to be applied to said person via said electrodes or magnetic stimulation coils, and wherein at least one of said electrodes or magnetic stimulation coils is adapted to be fixed near the sensory organ of said person.

12. The stimulation apparatus according to claim 11, wherein the sensory organ to which said electrode or magnetic stimulation coil is adapted to be fixed is formed by an eye of said person, by an ear of said person or by a touch sensory organ of said person.

13. The apparatus according to claim 12, wherein the optical sensory stimulation signal is adapted to be applied to an impaired region of the eye of said person.

14. The stimulation apparatus according to claim 1, wherein a memory is provided for storing a sensitivity chart indicating a sensitivity of areas of the sensory organ to a respective sensory stimulation signal.

15. The method stimulation apparatus according to claim 1,

wherein a spontaneous electroencephalogram (EEG) signal of the person is recorded;

wherein the frequency of the actual alpha brain wave activity of the person is analyzed; and

wherein the electrical stimulation signal used to stimulate the sensory organ of the person is based on the recorded spontaneous electroencephalogram (EEG) signal.