Neural stimulation systems, devices and methods

• US 8,706,212 B2
• Filed: 12/13/2006
• Issued: 04/22/2014
• Est. Priority Date: 12/13/2006
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Ternes, David, Kramer, Andrew P., Libbus, Imad, Stahmann, Jeffrey E.
• Primary Examiner(s): Bertram, Eric D.
• Application Number:
  US11/610,234
• Publication Number:
  US 20080147140A1
• Time in Patent Office: 2,687 Days
• Field of Search: 607/2
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36078 Inducing or controlling sleep or relaxation non-implantable stimulator A61M21/00
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: A61N 1/36117 for treating hypertension
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/39622 Pacing therapy
• CPC Class Codes: A61N 1/39624 Pain reduction therapy
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

Various system embodiments comprise circuitry to determine when an arrhythmia has terminated, and a neural stimulator adapted to temporarily deliver a neural stimulation therapy to assist with recovering from the arrhythmia in response to termination of the arrhythmia.

Claims

1. A system, comprising:

circuitry adapted to determine when an arrhythmia has terminated; and

a neural stimulator adapted to respond to termination of the arrhythmia by initiating a programmed neural stimulation therapy, wherein the programmed neural stimulation therapy has a programmed duration and is programmed to deliver a plurality of neural stimulation pulses, and wherein the programmed neural stimulation therapy is a programmed response to the termination of the arrhythmia to assist with recovering from the arrhythmia.

2. The system of claim 1, further comprising:

circuitry adapted to detect an arrhythmia; and

a pulse generator to deliver an arrhythmia therapy to terminate the arrhythmia.

3. The system of claim 2, wherein the pulse generator is adapted to deliver an anti-arrhythmia shock or anti-arrhythmia pacing.

4. The system of claim 1, wherein the neural stimulator is adapted to chronically deliver a neural stimulation signal as part of a chronic therapy and temporarily deliver the programmed neural stimulation therapy to assist with recovering from the arrhythmia.

5. The system of claim 4, wherein the neural stimulator is adapted to respond to the termination of the arrhythmia by temporarily withdrawing the neural stimulation signal delivered as part of the chronic therapy.

6. The system of claim 1, further comprising an arrhythmia detector adapted to provide a signal indicative that an arrhythmia is detected, the neural stimulator being adapted to deliver a pretherapy neural stimulation signal in preparation for an arrhythmia therapy in response to the signal indicative that the arrhythmia is detected.

7. The system of claim 6, wherein the arrhythmia therapy includes an anti-arrhythmia shock therapy, and the pretherapy neural stimulation signal includes a neural stimulation therapy to reduce pain associated with the antiarrhythmia shock therapy.

8. The system of claim 6, wherein the arrhythmia therapy includes an anti-arrhythmia shock therapy, and the pre-therapy neural stimulation signal includes a neural stimulation therapy to lower a defibrillation threshold.

9. The system of claim 6, wherein the arrhythmia therapy includes an antitachycardia pacing, and the pretherapy neural stimulation signal includes a neural stimulation therapy to modify the arrhythmia in preparation for antitachycardia pacing.

10. The system of claim 1, wherein the circuitry adapted to determine when the arrhythmia has terminated includes circuitry adapted to sense a delivered anti-arrhythmia shock.

11. The system of claim 1, wherein the circuitry adapted to determine when the arrhythmia has terminated includes communication circuitry adapted to receive a communication signal indicating that the arrhythmia has been terminated.

12. The system of claim 1, wherein the circuitry adapted to determine when the arrhythmia has terminated includes circuitry adapted to sense arrhythmic episodes, and sense the termination of non-sustained or self-terminating arrhythmias.

13. A method, comprising:

determining that an arrhythmia has terminated; and

upon termination of the arrhythmia, initiating a programmed neural stimulation therapy, wherein the programmed neural stimulation therapy has a programmed duration and is programmed to deliver a plurality of neural stimulation pulses, and wherein the programmed neural stimulation therapy is a programmed response to the termination of the arrhythmia to assist with recovering from the arrhythmia.

14. The method of claim 13, further comprising chronically performing a prophylactic neural stimulation therapy before the programmed neural stimulation therapy to assist with recovering from the arrhythmia, or after the programmed neural stimulation therapy to assist with recovering from the arrhythmia, or before and after the programmed neural stimulation therapy to assist with recovering from the arrhythmia.

15. The method of claim 13, wherein initiating the programmed neural stimulation therapy includes initiating at least a two stage neural stimulation therapy.

16. The method of claim 15, wherein the at least the two stage neural stimulation therapy includes one stage programmed to withdraw neural stimulation after arrhythmia termination, and a subsequent stage programmed to deliver neural stimulation.

17. The method of claim 13, further comprising delivering pretherapy neural stimulation in preparation for an arrhythmia therapy.

18. The method of claim 13, further comprising:

chronically performing a prophylactic neural stimulation therapy;

detecting an arrhythmia;

upon detecting the arrhythmia, delivering pretherapy neural stimulation in preparation for an arrhythmia therapy;

delivering the arrhythmia therapy;

upon arrhythmia termination, initiating and temporarily delivering the programmed neural stimulation therapy to assist with recovering from the arrhythmia; and

chronically performing the prophylactic neural stimulation therapy after temporarily delivering the neural stimulation therapy to assist with recovering from the arrhythmia.

19. The method of claim 18, wherein delivering pretherapy neural stimulation includes delivering neural stimulation in anticipation of pain associated with the arrhythmia therapy or to lower a defibrillation threshold when the arrhythmia therapy includes an antitachycardia shock, or includes delivering neural stimulation to make an arrhythmia more amenable to an antitachycardia pacing (ATP) therapy.