Cosmetic or dermopharmaceutical composition comprising an euglena extract

• US 8,741,357 B2
• Filed: 01/13/2006
• Issued: 06/03/2014
• Est. Priority Date: 01/14/2005
• Status: Active Grant

• Current Assignee: Sederma, Co.
• Original Assignee: Sederma SAS (Croda International Plc (Technology Investment Group))
• Inventors: Lintner, Karl, Mas Chamberlin, Claire, Mondon, Philippe, Lamy, Louis Franois
• Primary Examiner(s): LEITH, PATRICIA A
• Application Number:
  US11/795,330
• Publication Number:
  US 20090017147A1
• Time in Patent Office: 3,063 Days
• Field of Search: 424/725
• US Class Current: 424/725
• CPC Class Codes: A61K 8/9711 Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
• CPC Class Codes: A61K 8/9728 Fungi, e.g. yeasts
• CPC Class Codes: A61K 8/9767 Pinaceae [Pine family], e.g. pine or cedar
• CPC Class Codes: A61K 8/9771 Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61K 8/9794 Liliopsida [monocotyledons]
• CPC Class Codes: A61P 17/02 for treating wounds, ulcers, burns, scars, keloids, or the like
• CPC Class Codes: A61P 17/16 Emollients or protectives, e.g. against radiation
• CPC Class Codes: A61Q 17/00 Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/001 Preparations for care of the lips
• CPC Class Codes: A61Q 19/007 Preparations for dry skin
• CPC Class Codes: A61Q 19/06 for countering cellulitis
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations
• CPC Class Codes: A61Q 5/00 Preparations for care of the hair

Abstract

The invention provides a cosmetic or dermopharmaceutic composition containing an Euglena extract, its use to activate the cellular metabolism and in particular to protect and/or improve the state of the skin and to reduce the signs of ageing in particular and/or cutaneous fatigue.

Claims

1. A method of treating and/or reducing loss of skin elasticity or loss of skin firmness comprising topically applying to the skin of a subject in need thereof a cosmetic or dermopharmaceutical composition containing an amount of an Euglena gracilis extract sufficient to reconstitute intracellular ATP in the skin cells, generate IP₃ in the skin cells, or trigger release of intracellular calcium in the skin cells to which it is applied, and a dermatologically acceptable carrier, whereby said Euglena gracilis extract is prepared by culturing Euglena gracilis in a culture medium, lysing the Euglena gracilis, separating the solids from the liquid phase, and collecting said liquid phase whereby said liquid phase is the extract of Euglena gracilis, and wherein the Euglena gracilis extract includes a total phospholipid content of between about 0.002% (w/w) and about 5% (w/w).

2. The method according to claim 1, wherein said Euglena gracilis extract is present at a concentration from 0.01% (w/w) to 100% (w/w) by weight of the composition.

3. The method according to claim 2, wherein the Euglena gracilis extract is present at a concentration from 0.1% (w/w) to 30% (w/w) by weight of the composition.

4. The method according to claim 3, wherein the Euglena gracilis extract is present at a concentration from 0.5% (w/w) to 5% (w/w) by weight of the composition.

5. The method according to claim 1, wherein the cosmetic or dermopharmaceutical composition further comprises at least one skin care active.

6. The method according to claim 5, wherein the at least one skin care active is selected from the group consisting of peptidic compounds, vitamin A (retinol), vitamin E (tocopherol), alpha hydroxy acids (AHA), isoflavones, and active oxygen-generation inhibitors.

7. The method according to claim 1, wherein the cosmetic or dermopharmaceutical composition further comprises a skin anti-aging agent, anti-wrinkle agent, anti-atrophy agent, anti-oxidant or radical scavenger.

8. The method according to claim 1, wherein the Euglena extract is in the form of a solution, dispersion, emulsion, paste, powder, macrocapsule, microcapsule, nanocapsule, macrosphere, microsphere, nanosphere, liposome, oleosome, chylomicron, macroparticle, microparticle, nanoparticle, macrosponge, microsponge or nanosponge;

or wherein the extract is adsorbed on organic polymer powders, talcs, bentonites or other inorganic supports.

9. The method according to claim 1, wherein the composition is in the form of a cream, lotion, ointment, milk, gel, emulsion, dispersion, solution, suspension, cleanser, foundation, anhydrous preparation, stick, lipstick, body or bath oil, shower or bath gel, cream or lotion for care of the skin, sun-screen lotion, artificial tanning lotion, shaving cream or foam, aftershave lotion, mascara, nail varnish, serum, adhesive or absorbent material, transdermal patch, powder, emollient lotion, emollient milk, emollient cream, spray, bath or body oil, make-up, foundation tint base, pomade, colloid, compact or solid suspension, pencil, or sprayable formulation.

10. The method of claim 1 wherein said cosmetic or dermopharmaceutical composition is applied to the face of the subject.

11. The method of claim 10 wherein said cosmetic or dermopharmaceutical composition is applied to the lips of the subject.

12. The method of claim 10 wherein said cosmetic or dermopharmaceutical composition is applied to the eye area of the subject.

13. The method of claim 1 wherein said cosmetic or dermopharmaceutical composition is applied to stretch marks on the skin of the subject.

14. The method of claim 1 wherein said applying comprises continuously, topically applying to the subject via skin/textile contact.