Testosterone gel and method of use

  • US 8,741,881 B2
  • Filed: 03/14/2013
  • Issued: 06/03/2014
  • Est. Priority Date: 10/12/2005
  • Status: Active Grant
First Claim
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1. A method of treating hypogonadism in a human male comprising applying a therapeutically effective dose of a gel pharmaceutical composition consisting of:

  • a) 1.3% to 1.7% (w/w) testosterone;

    b) 0.9% to 1.0% (w/w) isopropyl myristate;

    c) 67.0% to 74.0% (w/w) of a lower alcohol selected from the group consisting of methanol, ethanol, n-propanol, isopropanol, n-butanol, isobutanol, sec-butanol, and tert-butanol;

    d) 0.6% to 1.4% (w/w) of a gelling agent, which gelling agent is an anionic polymer that has been neutralized with an amount of neutralizer sufficient to form a gel; and

    e) water,to an area of skin of the human male.

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