Cartridge system for delivery of medicament

• US 8,771,229 B2
• Filed: 12/01/2011
• Issued: 07/08/2014
• Est. Priority Date: 12/01/2011
• Status: Active Grant

• Current Assignee: PicoLife Technologies, LLC
• Original Assignee: PicoLife Technologies, LLC
• Inventors: Amirouche, Farid, Attar, Arash N., Cantwell, Matthew L.
• Primary Examiner(s): STIGELL, THEODORE J
• Application Number:
  US13/308,899
• Publication Number:
  US 20130144214A1
• Time in Patent Office: 950 Days
• Field of Search: 604131-132, 604151-153, 417/477.2
• US Class Current: 604/153
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/1422 with double acting or multiple pistons
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407

Abstract

A cartridge system for delivery of medicament includes as membrane placed between two disk magnets that are housed within pump body inserts. The pump body inserts having flow channels and fluid openings are between two inlet/outlet members. The inlet/outlet members each having a fluid outlet component and fluid openings are securely engaged to two reservoirs containing fluid medicaments.

Claims

1. A cartridge system, comprising:

a first reservoir and a second reservoir, wherein the first reservoir and the second reservoir each include a body having;

a top end, a bottom end, an inner wall, and an outer wall enclosing a reservoir space;

an opening formed in the top end, the opening being encircled by the outer wall and the inner wall, and the outer and inner walls projecting upwardly at the top end to form a female portion;

a first inlet/outlet member having a male portion configured to engage the female portion of the first reservoir, the first inlet/outlet member having a fluid receiving opening, a fluid discharge opening, and a fluid outlet component, the fluid receiving opening of the first inlet/outlet member in fluid communication with the first reservoir, and the fluid outlet component of the first inlet/outlet member in fluid communication with the fluid discharge opening of the first inlet/outlet member;

a second inlet/outlet member having a male portion configured to engage the female portion of the second reservoir, the second inlet/outlet member having a fluid receiving opening, a fluid discharge opening, and a fluid outlet component, the fluid receiving opening of the second inlet/outlet member in fluid communication with the second reservoir, and the fluid outlet component of the second inlet/outlet member in fluid communication with the fluid discharge opening of the second inlet/outlet member;

a first pump body insert having a fluid receiving opening, a fluid discharge opening, a plurality of inlet channels, and a plurality of outlet channels, the fluid receiving opening of the first pump body insert in fluid communication with the plurality of inlet channels of the first pump body insert, the plurality of inlet channels of the first pump body insert in fluid communication with the plurality of outlet channels of the first body insert, and the plurality of outlet channels of the first pump body insert in fluid communication with the fluid discharge opening of the first pump body insert;

a second pump body insert having a fluid receiving opening, a fluid discharge opening, a plurality of inlet channels, and a plurality of outlet channels, the fluid receiving opening of the second pump body insert in fluid communication with the plurality of inlet channels of the second pump body insert, the plurality of inlet channels of the second pump body insert in fluid communication with the plurality of outlet channels of the second pump body insert, and the plurality of outlet channels of the second pump body insert in fluid communication with the fluid discharge opening of the second pump body insert;

a pump membrane positioned between the first pump body insert and the second pump body insert; and

a plurality of magnets, at least one of the plurality of magnets having a distal end, a proximal end, and a body extending between the distal and proximal ends, and the proximal end being in contact with the pump membrane and the distal end being housed within at least one of the first and second pump body inserts,

wherein the fluid receiving opening of the first pump body insert is in fluid communication with the fluid receiving opening of the first inlet/outlet member, and the fluid discharge opening of the first pump body insert is in fluid communication with the fluid discharge opening of the first inlet/outlet member, and

wherein the fluid receiving opening of the second pump body insert is in fluid communication with the fluid receiving opening of the second inlet/outlet member, and the fluid discharge opening of the second pump body insert is in fluid communication with the fluid discharge opening of the second inlet/outlet member.

2. The cartridge system of claim 1, further comprising:

a plurality of valve membranes, wherein at least one of the valve membranes is located between the fluid receiving opening of the first pump body insert and the first inlet/outlet member, at least one, of the valve membranes is located between the fluid receiving opening of the second pump body insert and the second inlet/outlet member, at least one of the valve membranes is located between the fluid discharge opening of the first pump body insert and the first inlet/outlet member, and at least one of the valve membranes is located between the fluid discharge opening of the second pump body insert and the second inlet/outlet member.

3. The cartridge system of claim 1, wherein the fluid outlet component of the first inlet/outlet member and the fluid outlet component of the second inlet/outlet member each has a distal end, a proximal end, and a cylindrical body connecting the respective distal and the proximal ends, wherein the proximal end of the fluid outlet component of the first inlet/outlet member is in fluid communication with the fluid discharge opening of the first inlet/outlet member, and wherein the proximal end of the fluid outlet component of the second inlet/outlet member is in fluid communication with the fluid discharge of the second inlet/outlet member.

4. The cartridge system of claim 1, further comprising:

a plurality of reservoir shells; and

an insulation layer provided within at least one of the plurality of reservoir shells, wherein the first reservoir and the second reservoir are each mounted within a said reservoir shell.

5. The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the first reservoir and secures the first reservoir to the male portion of the first inlet/outlet member.

6. The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the first reservoir, and the cap and the first reservoir are contained within at least one shell.

7. The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the second reservoir and secures the second reservoir to the male portion of the second inlet/outlet member.

8. The cartridge system of claim 4, further comprising a cap, wherein the cap is coupled to the inner wall of the second reservoir near the male portion of the second inlet/outlet member.

9. The cartridge system of claim 4, wherein the first reservoir and the second reservoir are mounted within the same reservoir shell.

10. The cartridge system of claim 4, wherein the first reservoir and the second reservoir are mounted within different reservoir shells.

11. The cartridge system of claim 1, wherein the first and the second reservoir are located within a housing unit.

12. The cartridge system of claim 11, wherein the housing unit is made of Acrylonitrile Butadiene Styrene Medical Grade.

13. The cartridge system of claim 1, wherein the first reservoir contains a first fluid medicament and the second reservoir contains a second fluid medicament.

14. The cartridge system of claim 13, wherein the first reservoir and the second reservoir are pre-filled with the first fluid medicament and the second fluid medicament, respectively.

15. The cartridge system of claim 13, wherein the first fluid medicament includes insulin and the second fluid medicament includes glucagon.

16. The cartridge system of claim 1, wherein the pump membrane is prestressed and is made of silicone.

17. The cartridge system of claim 1, wherein the plurality of magnets are made of gold-plated neodymium-iron-boron.

18. The cartridge system of claim 1, wherein the first and second reservoirs are made of at least one material from the group consisting of silicone and Medical Grade Polyisoprene.

19. The cartridge system of claim 1, further comprising an orifice located on at least one of the first inlet/outlet member and the second inlet/outlet member.