System and methods for sliding-scale cardiac event detection

• US 8,781,566 B2
• Filed: 02/12/2008
• Issued: 07/15/2014
• Est. Priority Date: 03/01/2006
• Status: Active Grant

• Current Assignee: Angel Medical Systems, Inc.
• Original Assignee: Angel Medical Systems, Inc.
• Inventors: John, Michael Sasha, Fischell, David R., Hopenfeld, Bruce
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): GHAND, JENNIFER LEIGH-STEWAR
• Application Number:
  US12/068,776
• Publication Number:
  US 20080188763A1
• Time in Patent Office: 2,345 Days
• Field of Search: 600/509, 600/516
• US Class Current: 600/516
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period

Abstract

A system for the detection of cardiac events occurring in a human patient is disclosed to include at least two electrodes for obtaining an electrical signal from a patient'"'"'s heart. At least two electrodes are included in the system for obtaining an electrical signal from a patient'"'"'s heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal. The system determines the presence of a cardiovascular condition by applying a sliding scale rule to heart signal feature values. When the cardiovascular condition is ischemia, the ST segment may be analyzed. A sliding scale is applied to ST segment shifts such that when the magnitudes of ST segment shifts are relatively small, a larger number of beats is required to detect ischemia compared to the case when the magnitudes of ST shifts are large.

Claims

1. An implantable device for tracking the cardiovascular condition of a human patient, the device including:

an electrode adapted for placement inside a human patient to sense the electrical signal from the patient'"'"'s heart, the electrical signal being an electrogram which consists of a multiplicity of beats;

a digital processor configured to;

acquire the electrogram and compute from the electrogram a plurality of values of a heart signal feature;

compute both first and second aspects pertaining to the plurality of values of the heart signal feature within the acquired electrogram, wherein the first and second aspects are at least partially independent of one another and are defined as a magnitude of the heart signal feature and time duration over which said heart signal feature is computed, respectively; and

detect a cardiovascular condition by applying a test to the plurality of values of the heart signal feature within the acquired electrogram, wherein the test is at least partially based on a sliding scale such that the first and second aspects of the plurality of values vary in accordance with one another.

2. The implantable device of claim 1 wherein the heart signal feature is ST segment shift.

3. The implantable device of claim 1 wherein the sliding scale is implemented by applying a threshold to the first aspect such that the value of the threshold depends on the value of the second aspect.

4. The implantable device of claim 1 wherein the sliding scale is implemented by forming a weighted sum of first and second cardiac state parameters, wherein each of the first and second cardiac state parameters is a function of the values of both the first and second aspects.

5. The implantable device of claim 4 wherein the first state parameter is equal to the number of heart beats that a heart signal feature value of the plurality of values of the heart signal feature exceeded a first threshold, and the second state parameter is equal to the number of heart beats that a heart signal feature value exceeded a second threshold.

6. The implantable device of claim 1 wherein the sliding scale is implemented by applying first and second thresholds to first and second cardiac state parameters, wherein each of the first and second cardiac state parameters is a function of the values of both the first and second aspects, and wherein the cardiac condition is detected if either of the first or second cardiac state parameter exceeds the corresponding first or second threshold.

7. The implantable device of claim 6 wherein the first state parameter is equal to the number of heart beats that a heart signal feature value of the plurality of values of the heart signal feature exceeded a first threshold, and the second state parameter is equal to the number of heart beats that a heart signal feature value exceeded a second threshold.

8. The implantable device of claim 6 wherein the sliding scale is implemented by applying third and fourth thresholds to first and second cardiac state parameters, wherein the third and fourth thresholds are smaller than the first and second thresholds, respectively, and wherein the cardiac condition is detected if both the first and second cardiac state parameters exceeded the third and fourth thresholds, respectively.

9. An implantable device for tracking the cardiovascular condition of a human patient, the device including:

an electrode adapted for placement inside a human patient to sense an electrical signal from the patient'"'"'s heart, the electrical signal being an electrogram which consists of a multiplicity of beats, a digital processor configured to;

acquire the electrogram and to compute from the electrogram both a first plurality of values of a first heart signal feature and a second plurality of values of a second heart signal feature;

apply a test to the first plurality of values and the second plurality of values within the acquired electrogram, wherein the test is at least partially based on a sliding scale such that the first plurality of values and the second plurality of values vary in accordance with one another.

10. The implantable device of claim 9 wherein the first heart signal feature pertains to cardiac repolarization.

11. The implantable device of claim 10 wherein the first heart signal feature pertains to the ST segment.

12. The implantable device of claim 10 wherein the second heart signal feature pertains to cardiac activation.

13. The implantable device of claim 10 wherein the second heart signal feature pertains to cardiac repolarization, and wherein the first and second heart signal features pertain to different aspects of cardiac repolarization.