Aqueous liquid preparations and light-stabilized aqueous liquid preparations

  • US 8,784,789 B2
  • Filed: 07/30/2003
  • Issued: 07/22/2014
  • Est. Priority Date: 07/31/2002
  • Status: Active Grant
First Claim
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1. An aqueous liquid preparation consisting of, in an aqueous solution, an active ingredient consisting of (+)-(S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid or a pharmacologically acceptable acid addition salt thereof;

  • a water-soluble metal chloride in a light-stabilizing effective amount;

    water; and

    optionally at least one material selected from the group consisting of a buffer, a preservative, a chelating agent, and a flavor;

    wherein the metal chloride has a concentration selected from the range of a lower limit concentration of 0.2 w/v % and an upper limit concentration of 1.2 w/v %.

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