Controlled release and taste masking oral pharmaceutical composition

CAFC
  • US 8,784,888 B2
  • Filed: 09/14/2012
  • Issued: 07/22/2014
  • Est. Priority Date: 06/14/1999
  • Status: Expired due to Term
First Claim
Patent Images

1. A controlled release oral pharmaceutical composition consisting essentially of:

  • (1) a tablet core consisting essentially of;

    a) budesonide in an amount effective to treat intestinal inflammatory disease; and

    b) a macroscopically homogeneous composition comprising at least one lipophilic excipient, at least one amphiphilic excipient, and at least one hydrogel-forming hydrophilic excipient other than a gum, wherein said budesonide is dispersed in said macroscopically homogeneous composition; and

    (2) a coating on said tablet core, said coating consisting essentially of a gastro-resistant film.

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