Integrated system and method for treating disease using cognitive training and brain stimulation and computerized magnetic photoelectric stimulator (CMPES)

• US 8,805,516 B2
• Filed: 06/07/2013
• Issued: 08/12/2014
• Est. Priority Date: 09/13/2004
• Status: Active Grant

• Current Assignee: Neuronix Ltd.
• Original Assignee: Neuronix Ltd.
• Inventors: Bentwich, Jonathan
• Primary Examiner(s): MALAMUD, DEBORAH LESLIE
• Application Number:
  US13/912,868
• Publication Number:
  US 20130267761A1
• Time in Patent Office: 431 Days
• Field of Search: 607 1- 3, 607/45, 607 55- 57, 607/89, 607100-103, 607/115, 607/139, 607/142, 607/148, 607/154, 607155-156, 600/9, 600 11- 15, 600544-545
• US Class Current: 607/45
• CPC Class Codes: A61B 5/4088 Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
• CPC Class Codes: A61N 1/36025 for treating a mental or cerebral condition
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/36092 Mental training
• CPC Class Codes: A61N 2/002 in combination with another treatment
• CPC Class Codes: A61N 2/006 for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 5/0616 Skin treatment other than tanning
• CPC Class Codes: A61N 5/067 using laser light

Abstract

An integrated system and method for treatment of various diseases, including psychiatric, mental and brain disorders, which preferably combines personalized non-invasive neuronal brain stimulation together with appropriate personalized cognitive training, and which iteratively fine-tunes this treatment by monitoring specific cognitive and brain functions in response to the treatment. A novel brain stimulator device and method, Computerized Magnetic Photo-Electric Stimulator (CCMPES), is described, which integrates electromagnetic stimulation with laser stimulation to generate a magnetic photo-electric stimulation.

Claims

1. A method for treatment of Alzheimer'"'"'s disease in a patient, comprising:

stimulating at least one abnormal region of a brain of the patient with magnetic stimulation or with electric stimulation, using a non-invasive electromagnetic brain stimulator; and

concurrently administering a cognitive stimulation associated with the abnormal brain region of the patient, using a computerized cognitive brain stimulator.

2. The method according to claim 1, wherein said method further comprises analyzing alteration of a localized brain feature or a cognitive feature following said stimulating and administering steps, and modulating at least one of the steps of stimulating at least one abnormal region of a brain of the patient or administering a cognitive stimulation.

3. The method for treatment according to claim 1, wherein said stimulating step comprises stimulating at least one abnormal region of a brain of the patient with magnetic stimulation wherein said magnetic stimulation is carried out using a transcranial magnetic stimulator (TMS) or a repetitive transcranial magnetic stimulator (rTMS).

4. The method for treatment according to claim 1, wherein said administering step comprises administering memory-related stimulation to the patient.

5. A method for treatment of a neurodegenerative disease in a patient, comprising:

stimulating at least one region of a brain of the patient with magnetic stimulation or with electric stimulation, using a non-invasive electromagnetic brain stimulator, which at least one region is a specific brain region associated with said disease; and

concurrently administering a memory-related cognitive stimulation associated with a specific brain region of the patient, using a computerized cognitive brain stimulator.

6. The method according to claim 5, wherein said method further comprises analyzing alteration of a localized brain feature or a cognitive feature following said stimulating and administering steps, and modulating at least one of the steps of stimulating at least one region of a brain of the patient or administering a cognitive stimulation.

7. The method for treatment according to claim 5, wherein said stimulating step comprises stimulating at least one region of a brain of an individual with magnetic stimulation wherein said magnetic stimulation is carried out using a transcranial magnetic stimulator (TMS) or a repetitive transcranial magnetic stimulator (rTMS).