Method for inducing migration of adipose-derived adult stem cells

  • US 8,808,682 B2
  • Filed: 10/25/2010
  • Issued: 08/19/2014
  • Est. Priority Date: 10/23/2009
  • Status: Active Grant
First Claim
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1. A method for inducing the migration of adipose tissue-derived adult stem cells, the method comprising the steps of:

  • priming adipose tissue-derived adult stem cells by culturing the cells in medium with added adiponectin; and

    one or more factors selected from the group consisting ofTNF-α

    (tumor necrosis factor-α

    ), PDGF-AB (platelet derived growth factor AB)Rantes, SDF-1α

    (stromal cell-derived factor-1α

    ), and MCP-1 (monocyte chemoattractant protein-1); and

    administering a composition containing the primed adipose tissue-derived adult stem cells into an in vivo site which is not in direct contact with a disease site.

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