Use of TNF alpha inhibitor for treatment of erosive polyarthritis

  • US 8,808,700 B1
  • Filed: 03/28/2014
  • Issued: 08/19/2014
  • Est. Priority Date: 05/16/2005
  • Status: Active Grant
First Claim
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1. A method for treating erosive polyarthritis, comprising administering a human anti-TNFα

  • antibody to a human subject having erosive polyarthritis associated with psoriatic arthritis, ankylosing spondylitis or juvenile rheumatoid arthritis, wherein a modified Total Sharp Score (mTSS) of the subject is maintained or decreased following said treating as compared to baseline prior to said treating, and wherein the human anti-TNFα

    antibody comprises (1) a light chain variable region (LCVR) comprising the amino acid sequence of SEQ ID NO;

    1 and (2) a heavy chain variable region (HCVR) comprising the amino acid sequence of SEQ ID NO;

    2.

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