Methods of treating traveler's diarrhea and hepatic encephalopathy

  • US 8,829,017 B2
  • Filed: 03/31/2011
  • Issued: 09/09/2014
  • Est. Priority Date: 10/02/2008
  • Status: Active Grant
First Claim
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1. A method of treating a patient having hepatic encephalopathy (HE) comprising:

  • identifying a subject having Travelers'"'"' Diarrhea (TD) that also has hepatic insufficiency;

    determining if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s model end stage liver disease (MELD) score is 25 or greater; and

    administering between 1000 and 1200 mg of rifaximin daily and cautiously to the subject if the subject'"'"'s Child-Pugh score is Child-Pugh Class C or if the subject'"'"'s MELD score is 25 or greater.

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