Compositions and methods of making rapidly dissolving ionically masked formulations

  • US 8,840,924 B2
  • Filed: 03/04/2010
  • Issued: 09/23/2014
  • Est. Priority Date: 10/21/2005
  • Status: Active Grant
First Claim
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1. A compressed, orally disintegrating, controlled release taste-masked pharmaceutical composition comprising:

  • a coated drug-ion-exchange resin complex and a directly compressible, free-flowing pharmaceutical excipient,wherein the composition effectively masks an unpalatable taste associated with delivery of the drug,wherein the coated drug-ion-exchange resin complex is coated with a controlled release coating,and wherein the directly compressible, free-flowing pharmaceutical excipient aids in the liberation of the coated drug-resin complex in the mouth through disintegration.

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