Biocatalysts and methods for the synthesis of (;)-3-(1-aminoethyl)-phenol

  • US 8,852,900 B2
  • Filed: 06/16/2011
  • Issued: 10/07/2014
  • Est. Priority Date: 06/17/2010
  • Status: Active Grant
First Claim
Patent Images

1. An engineered polypeptide having transaminase activity comprising an amino acid sequence having at least 90% sequence identity to SEQ ID NO:

  • 2 and amino acid residue differences as compared to SEQ ID NO;

    2 at one or more positions selected from G18, K163, A235, P244, A323, A383, C424, and F427.

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