Inter dialytic monitoring device

• US 8,870,769 B2
• Filed: 05/23/2011
• Issued: 10/28/2014
• Est. Priority Date: 05/23/2011
• Status: Active Grant

• Current Assignee: Mozarc Medical US LLC
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Deshpande, Manish
• Primary Examiner(s): D'ANGELO, MICHAEL J
• Application Number:
  US13/113,175
• Publication Number:
  US 20120302848A1
• Time in Patent Office: 1,254 Days
• Field of Search: 600/345, 600/347, 600/365, 600/309
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/1427 Multiple blood sampling, e.g. at periodic or pre-established intervals
• CPC Class Codes: A61B 5/14528 invasively
• CPC Class Codes: A61B 5/15003 for venous or arterial blood
• CPC Class Codes: A61B 5/150229 Pumps for assisting the blood sampling
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/150992 Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves tubing connectors and couplings A61M39/00
• CPC Class Codes: A61B 5/155 Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals devices loaded with multiple lancets simultaneously A61B5/15146
• CPC Class Codes: A61B 5/157 Devices characterised by integrated means for measuring characteristics of blood
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 5/6866 Extracorporeal blood circuits, e.g. dialysis circuits
• CPC Class Codes: A61M 1/3609 Physical characteristics of the blood, e.g. haematocrit, urea
• CPC Class Codes: A61M 2230/20 Blood composition characteristics
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence

Abstract

An inter dialytic monitoring device is disclosed which monitors in vivo preselected parameters of blood content during an inter dialytic period to monitor patient health. The monitoring device is configured to extend through and releasably engage a catheter which has been placed within a patient to monitor a patient'"'"'s blood. A sensor is provided to detect the presence of selected analytes and to identify when preselected parameters have been reached.

Claims

1. An inter dialytic monitoring device comprising:

a sensory wire configured and dimensioned to extend through a lumen of a catheter, the sensory wire having a tip positioned to be exposed to blood flow within a patient, wherein the sensory wire defines a microchannel and the sensor is supported on an end of the sensory wire opposite to the tip, the microchannel extending from the tip to the sensor and back to the tip;

a sensor operably associated with the sensory wire and being adapted to detect the presence of a preselected analyte within a patient'"'"'s blood; and

an indicator operably associated with the sensor configured to provide an indication to a patient that preselected parameters have been reached regarding the preselected analyte.

2. The monitoring device according to claim 1, further including an ion-selective membrane covering the tip of the sensory wire, the ion-selective membrane being permeable to specific preselected analytes.

3. The monitoring device according to claim 2, wherein the sensor is supported on the tip of the sensory wire and is covered by the ion-selective membrane.

4. The monitoring device according to claim 1, wherein the indicator includes a light which illuminates when the preselected parameters have been reached.

5. The monitoring device according to claim 1, wherein the indicator includes a first light and a second light, the first light being illuminated when the preselected parameters have not been reached and the second light being illuminated when the preselected parameters have been reached.

6. The monitoring device according to claim 5, wherein the first light is green and the second light is red.

7. The monitoring device according to claim 1, wherein the microchannel includes a fluid which is circulated through the microchannel between the tip and the sensor.

8. The monitoring device according to claim 7, wherein the fluid is saline.

9. The monitoring device according to claim 7, wherein the sensor and the indicator are supported in a sensor device which is connected to the end of the sensory wire opposite to the tip.

10. The monitoring device according to claim 9, wherein the end of the sensory wire opposite to the tip includes a port for removably receiving the sensor device.

11. The monitoring device according to claim 10, wherein the sensor device includes a body and a removable cartridge, wherein the body defines a cavity for receiving the removable cartridge.

12. The monitoring device according to claim 11, wherein the body includes the mechanical and electrical components to pump fluid through the microchannel and to translate signals received from the sensor.

13. The monitoring device according to claim 11, wherein the removable cartridge supports the sensor.

14. The monitoring device according to claim 12, wherein the fluid circulating in the microchannel is originally contained within the removable cartridge.

15. The monitoring device according to claim 14, wherein the cartridge is disposable and the body of the sensor device which supports the indicator is reusable.

16. The monitoring device according to claim 9, wherein the sensor device includes removable test strips.

17. The monitoring device according to claim 1, wherein the preselected analyte is selected from the group consisting of glucose, sodium, potassium, urea, hematocrit, and oxygen saturation.

18. The monitoring device according to claim 1, further including a connector for securing the monitoring device to a catheter.

19. The monitoring device according to claim 1 wherein the sensory wire is adapted to be conducive to clot formation.