Administration device comprising indication unit and method for setting a dose

• US 8,870,830 B2
• Filed: 05/12/2010
• Issued: 10/28/2014
• Est. Priority Date: 11/13/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Remde, Axel
• Primary Examiner(s): Bosworth, Kami A
• Application Number:
  US12/778,634
• Publication Number:
  US 20110118700A1
• Time in Patent Office: 1,630 Days
• Field of Search: 604/66, 604/131, 604/151, 604/181, 604/183, 604/186, 604207-211, 604/890.1, 604/500, 604/503, 604/504, 604506-508, 604/511, 604/512
• US Class Current: 604/207
• CPC Class Codes: A61M 2005/3125 specific display means, e.g. to indicate dose setting
• CPC Class Codes: A61M 2005/3126 Specific display means related to dosing
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 5/31525 Dosing burettes, pipettes B01L3/02

Abstract

An administration device for the administration of a liquid drug in adjustable doses may comprise an injection unit and an electronic indication unit. The injection unit may comprise a dosing mechanism and a manually operated dose setting component. The manually operated dose setting component may adjust the dosing mechanism to administer an administration dose amount of the liquid drug. The electronic indication unit may indicate a relationship between the administration dose amount and a target dose amount. A method for setting a dose of a liquid drug for administration may comprise providing an administration device, operating a manually operated dose setting component of the administration device, and continuing to operate the dose setting component until an electronic indication unit indicates that the administration dose amount is equal to the target dose amount.

Claims

1. An administration device for administering a liquid drug in adjustable doses, the administration device comprising:

an injection unit having a dosing mechanism and a manually operated dose setting component that sets an administration dose amount of the liquid drug to be administered by the dosing mechanism; and

an electronic indication unit comprising a display that graphically indicates before administration of the liquid drug a dose amount deviation equal to the difference of the administration dose amount set using the dose setting component and a target dose amount stored in or entered into the administration device.

2. The administration device of claim 1, wherein the electronic indication unit further comprises a warning indicator that warns after administration of the liquid drug that the administration dose amount did not equal the target dose amount, the warning indicator being selected from the group consisting of an optical indicator, an acoustic indicator, a tactile indicator, and combinations thereof.

3. The administration device of claim 1, further comprising a data interface.

4. The administration device of claim 3, wherein the data interface transmits the target dose amount to the administration device from an external device.

5. The administration device of claim 1, wherein the administration device is configured to be handheld during administration of the liquid drug.

6. The administration device of claim 1, further comprising:

an injection module comprising the injection unit, the electronic indication unit, an injection module data interface, and an injection module housing; and

a supplementary module comprising a supplementary module data interface and a supplementary module housing,

wherein the supplementary module data interface transmits the target dose amount to the injection module data interface.

7. The administration device of claim 1, further comprising:

an injection module comprising the injection unit, an injection module data interface, and an injection module housing; and

a supplementary module comprising the electronic indication unit, a supplementary module data interface, and a supplementary module housing,

wherein the injection module data interface transmits an administration dose amount to the supplementary module data interface.

8. The administration device of claim 1, wherein the target dose amount is stored in a memory disposed in the administration device.

9. The administration device of claim 1, further comprising one or more data entry component.

10. The administration device of claim 9, further comprising a dose calculator for calculating a calculated dose amount D_calc based on therapy related data.

11. The administration device of claim 10, wherein the therapy related data comprise a carbohydrate amount, a blood glucose value, or both.

12. The administration device of claim 10, further comprising a carbohydrate amount database operatively coupled to the dose calculator.

13. The administration device of claim 1, further comprising a blood glucose meter.

14. The administration device of claim 1, wherein the display indicates before administration of the liquid drug a graduated dose scale showing an administration dose mark corresponding to the administration dose amount and a target dose mark corresponding to the target dose amount, whereby the dose amount deviation is graphically indicated from the relative positions of the administration dose mark and the target dose mark.

15. The administration device of claim 14, wherein the graduated dose scale has a range from the target dose amount plus 2.0 IU to the target dose amount minus 2.0 IU and the target dose mark is located in the middle of the graduated dose scale.

16. The administration device of claim 1, wherein:

the injection unit comprises a housing and a release key on the housing;

the dose setting component is a dose setting knob having a retracted position inside the housing and an extended position extended outside the housing, the dose setting knob being normally in the retracted position until the release key is pressed.

17. The administration device of claim 16, wherein the dose setting knob is rotatable only in the extended position and rotation of the dose setting knob sets the administration dose amount.

18. The administration device of claim 16, further comprising an electronics module that supplies power to the electronic indication unit, the electronics module being configured to change from a standby mode to a regular operation mode when the dose setting knob is placed into the extended position.

19. A method for setting a dose of a liquid drug for administration to a patient, the method comprising:

providing an administration device, the administration device comprising an injection unit and an electronic indication unit, the injection unit having a dosing mechanism and a manually operated dose setting component that sets an administration dose amount of the liquid drug to be administered by the dosing mechanism, the electronic indication unit comprising a display that graphically indicates before administration of the liquid drug a dose amount deviation equal to the difference of the administration dose amount set using the dose setting component and a target dose amount stored in or entered into the administration device;

operating the manually operated dose setting component to set the administration dose amount relative to the target dose amount; and

determining the relationship of the administration dose amount relative to the target dose amount from the electronic indication unit.

20. The method of claim 19, wherein the administration device further comprises a memory and the target dose amount is stored in the memory.

21. The method of claim 19, wherein the administration device further comprises one or more data entry component, the method further comprising manipulating the one or more data entry component to enter the target dose amount into the administration device.