Prosthetic valve for transluminal delivery

• US 8,876,896 B2
• Filed: 12/07/2011
• Issued: 11/04/2014
• Est. Priority Date: 11/17/1999
• Status: Expired due to Term

• Current Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: Seguin, Jacques, Brtlein, Georg
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): SCHILLINGER, ANN M
• Application Number:
  US13/313,556
• Publication Number:
  US 20120143316A1
• Time in Patent Office: 1,063 Days
• Field of Search: 623 111- 154
• US Class Current: 623/2.18
• CPC Class Codes: A61B 17/0218 for minimally invasive surgery A61B17/0281, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2/2409 Support rings therefor, e.g. for connecting valves to tissue annuloplasty rings A61F2/2442
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2427 Devices for manipulating or deploying heart valves during implantation
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2436 Deployment by retracting a sheath
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2002/91558 connected peak to peak
• CPC Class Codes: A61F 2002/91591 Locking connectors, e.g. using male-female connections
• CPC Class Codes: A61F 2210/0023 operated at different temperatures whilst inside or touching the human body, heated or cooled by external energy source or cold supply
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: A61F 2230/0067 : conical
• CPC Class Codes: A61F 2230/0078 : hyperboloidal
• CPC Class Codes: A61F 2250/0003 : having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0039 : differing in diameter
• CPC Class Codes: A61F 2250/0048 : differing in mechanical expandability, e.g. in mechanical, self- or balloon expandability
• CPC Class Codes: A61F 2250/0069 : Sealing means

Abstract

A prosthetic valve comprises a valve assembly having a base, a plurality of leaflets, and commissures. The valve also comprises a support stent having a plurality of expandable cells and a plurality of longitudinal struts. The support stent is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the prosthetic valve is positioned in situ. The support stent supports the base. The commissures of the valve assembly are secured at the longitudinal struts and adjacent one or more of the expandable cells. The longitudinal struts of the support stent further comprise a plurality of holes, and the plurality of leaflets are secured to the longitudinal struts via threads passing through the plurality of holes.

Claims

1. A prosthetic valve comprising:

a valve assembly comprising a base, a plurality of leaflets, and commissures;

a support stent comprising

a first row defining a first plurality of expandable cells;

a second row defining a second plurality of expandable cells; and

a plurality of longitudinal struts each comprising a proximal end portion and a distal end portion,

wherein the first row is directly connected to the proximal end portion of each of the plurality of longitudinal struts,

wherein the second row is directly connected to the distal end portion of each of the plurality of longitudinal struts,

wherein the support stent is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the prosthetic valve is positioned in situ,

wherein the support stent supports the base,

wherein the longitudinal struts of the support stent further comprise a plurality of holes, wherein the plurality of holes are entirely distal to the first row, and

wherein the commissures of the valve assembly are secured directly to the longitudinal struts via threads passing through both the plurality of holes and the commissures.

2. The prosthetic valve of claim 1, wherein the support stent is self-expanding.

3. The prosthetic valve of claim 1, wherein the support stent is balloon expandable.

4. The prosthetic valve of claim 1, wherein the support stent is configured to press radially against the native valve leaflets to hold the native valve leaflets against walls of the native valve annulus and/or against walls of an adjacent lumen to thereby prevent the native valve leaflets from obstructing the native valve annulus.

5. The prosthetic valve of claim 1, wherein the plurality of holes have a curved contoured portion.

6. A prosthetic valve comprising:

a valve assembly comprising an inlet, a plurality of leaflets, and commissural points;

a support stent comprising

a mesh-like construction comprising a plurality of expandable cells; and

a plurality of longitudinal support beams each comprising a proximal end portion directly connected to at least one of the plurality of expandable cells and a distal end portion directly connected to at least one of the plurality of expandable cells,

wherein the support stent is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the prosthetic valve is positioned in situ,

wherein the support stent supports the inlet,

wherein the longitudinal support beams of the support stent define a plurality of openings, wherein the plurality of openings are entirely distal to at least one of the plurality of expandable cells, and

wherein the plurality of commissure points are secured directly to the longitudinal support beams via threads passing through both the plurality of holes and the commissure points.

7. The prosthetic valve of claim 6, wherein the support stent is self-expanding.

8. The prosthetic valve of claim 6, wherein the support stent is balloon expandable.

9. The prosthetic valve of claim 6, wherein the support stent is configured to press radially against the native valve leaflets to hold the native valve leaflets against walls of the native valve annulus and/or against walls of an adjacent lumen to thereby prevent the native valve leaflets from obstructing the native valve annulus.

10. The prosthetic valve of claim 6, wherein the plurality of openings have a curved contoured portion.