Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)

CAFC
  • US 8,883,983 B2
  • Filed: 04/24/2014
  • Issued: 11/11/2014
  • Est. Priority Date: 08/23/2007
  • Status: Active Grant
First Claim
Patent Images

1. An isolated monoclonal antibody that binds an epitope on hPCSK9 comprising one or more of residues 207, 208, 162, 164, 167, 132, 351, 390, 413, 123, 129, 311, 313, or 337 of SEQ ID NO:

  • 1, and wherein the monoclonal antibody blocks binding of PCSK9 to LDLR.

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